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Πλοήγηση ανά Θέμα "Chemokines"

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    • Acquisition of optimal TFH cell function is defined by specific molecular, positional, and TCR dynamic signatures 

      Padhan K., Moysi E., Noto A., Chassiakos A., Ghneim K., Perra M.M., Shah S., Papaioannou V., Fabozzi G., Ambrozak D.R., Poultsidi A., Ioannou M., Fenwick C., Darko S., Douek D.C., Sekaly R.-P., Pantaleo G., Koup R.A., Petrovas C. (2021)
      The development of follicular helper CD4 T (TFH) cells is a dynamic process resulting in a heterogenous pool of TFH subsets. However, the cellular and molecular determinants of this heterogeneity and the possible mechanistic ...

    • Conformational properties of HIV-1 gp120/V3 immunogenic domains 

      Galanakis, P. A.; Spyroulias, G. A.; Rizos, A.; Samolis, P.; Krambovitis, E. (2005)
      Infection of target host cells by the human immunodeficiency virus-1 (HIV-1) is a multi-step process involving a series of conformational changes in the viral gp120 and gp41 proteins. Gp120 binding to the main cell receptor, ...

    • Interleukin 21 controls mRNAand MicroRNA expression in CD40-activated chronic lymphocytic leukemia cells 

      De Cecco L., Capaia M., Zupo S., Cutrona G., Matis S., Brizzolara A., Orengo A.M., Croce M., Marchesi E., Ferrarini M., Canevari S., Ferrini S., Speletas M. (2015)
      Several factors support CLL cell survival in the microenvironment. Under different experimental conditions, IL21 can either induce apoptosis or promote CLL cell survival. To investigate mechanisms involved in the effects ...