Πλοήγηση ανά Θέμα "CATALYTIC SUBUNIT"
Αποτελέσματα 1-6 από 6
-
Correlation of promoter hypermethylation in hTERT, DAPK and MGMT genes with cervical oncogenesis progression
(2009)DNA hypermethylation occurs during the multi-step process of cervical carcinogenesis. We investigated whether the methylation status in the promoter region of a potential oncogene, the human telomerase reverse transcriptase ... -
Leptin as a critical regulator of hepatocellular carcinoma development through modulation of human telomerase reverse transcriptase
(2010)Background: Numerous epidemiological studies have documented that obesity is associated with hepatocellular carcinoma (HCC). The aim of this study was to investigate the biological actions regulated by leptin, the obesity ... -
Predictive value of telomerase reverse transcriptase expression in patients with high risk superficial bladder cancer treated with adjuvant BCG immunotherapy
(2009)We conducted a prospective study to determine whether expression of telomerase reverse transcriptase (hTERT) is associated with recurrence-free-survival (RFS) or development of invasive disease in patients with high risk ... -
Quantitative determination of human telomerase reverse transcriptase messenger RNA expression in prematignant cervical lesions and correlation with human papittomavirus load
(2006)Expression Of human telomerase reverse transcriptase (hTERT) messenger RNA (mRNA) and human papillomavirus (HPV)-16 load were quantified using real-time polymerase chain reaction and correlated with cytological findings ... -
Real-time quantification of human telomerase reverse transcriptase mRNA in liver tissues from patients with hepatocellular cancer and chronic viral hepatitis
(2007)We determined, for the first time, the human telomerase reverse transcriptase (hTERT) mRNA expression, using real-time quantitative PCR, in liver tissues from patients with hepatocellular cancer (HCC; n = 13), chronic ... -
Telomerase reverse transcriptase mRNA expression in peripheral lymphocytes of patients with chronic HBV and HCV infections
(2005)Telomerase activity is present at low levels in peripheral lymphocytes (PL) and is upregulated upon activation, possibly protecting PL from telomere shortening. As decreased telomere length is considered a sign of cellular ...