• BAFF receptor polymorphisms and deficiency in humans 

      Sevdali E., Block Saldana V., Speletas M., Eibel H. (2021)
      The BAFF-receptor (BAFFR) is a member of the TNF-receptor family. It is expressed only by B cells and binds BAFF as single ligand, which activates key signaling pathways regulating essential cellular functions, including ...
    • BAFF/APRIL system is functional in B-cell acute lymphoblastic leukemia in a disease subtype manner 

      Sevdali E., Katsantoni E., Smulski C.R., Moschovi M., Palassopoulou M., Kolokotsa E.N., Argentou N., Giannakoulas N., Adamaki M., Vassilopoulos G., Polychronopoulou S., Germenis A.E., Eibel H., Speletas M. (2019)
      [No abstract available]
    • Immunotherapy of systemic sclerosis 

      Katsiari C.G., Simopoulou T., Alexiou I., Sakkas L.I. (2018)
      Systemic sclerosis (SSc) is a chronic systemic disease characterized by microvasculopathy, immune activation, and extensive collagen deposition. Microvasculopathy and immune activation occur very early in the disease ...
    • Systemic sclerosis: New evidence re-enforces the role of B cells 

      Sakkas L.I., Bogdanos D.P. (2016)
      Systemic sclerosis (SSc) is characterized by widespread fibrosis, microangiopathy (vasospasms and stenosis), and formation of autoantibodies. T cell activation has been shown to contribute to fibrosis and microvasculopathy ...
    • TNFRSF13C/BAFFR P21R and H159Y polymorphisms in multiple sclerosis 

      Ntellas P., Dardiotis E., Sevdali E., Siokas V., Aloizou A.-M., Tsinti G., Germenis A.E., Hadjigeorgiou G.M., Eibel H., Speletas M. (2020)
      Recent studies implicate B cells in multiple sclerosis (MS) pathogenesis, and consequently, several molecules participating in B cell survival and proliferation, including B-cell activating factor (BAFF), have recently ...