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Amplification of Echoviruses genomic regions by different RT-PCR protocols - a comparative study

Kottaridi, C.; Bolanaki, E.; Markoulatos, P. (2004)

In the present report, the results of a comparative study in the detection of all Echoviruses reference strains as well as of 38 clinical isolates are presented. Using RT-PCR with already published primer pairs (UG(52)-UC53, ...

Anti-cancer activity of a novel palladium(II) complex on human breast cancer cells in vitro and in vivo

Ulukaya, E.; Ari, F.; Dimas, K.; Ikitimur, E. I.; Guney, E.; Yilmaz, V. T. (2011)

Anti-cancer effects of a newly-synthesized palladium(II) complex, [Pd(sac)(terpy)](sac)center dot 4H(2)O (sac = saccharinate, and terpy = 2,2':6',2 ''-terpyridine), were tested against human breast cancer cell lines, MCF-7 ...

Anvirzel (TM) in combination with cisplatin in breast, colon, lung, prostate, melanoma and pancreatic cancer cell lines

Apostolou, P.; Toloudi, M.; Chatziioannou, M.; Ioannou, E.; Knocke, D. R.; Nester, J.; Komiotis, D.; Papasotiriou, I. (2013)

Background: Platinum derivatives are used widely for the treatment of many cancers. However, the toxicity that is observed makes imperative the need for new drugs, or new combinations. Anvirzel (TM) is an extract which has ...

Assessment of Oxidative Stress in Septic and Obese Patients Using Markers of Oxidation-reduction Potential

Spanidis, Y.; Goutzourelas, N.; Stagos, D.; Kolyva, A. S.; Gogos, C. A.; Bar-Or, D.; Kouretas, D. (2015)

Background/ Aim: The novel static (sORP) and capacity (cORP) oxidation-reduction potential markers were examined for assessing oxidative stress in plasma of patients with sepsis. Moreover, the possible effect of obesity-induced ...

Bayesian estimation of the true prevalence of Mycobacterium avium subsp paratuberculosis infection in Cypriot dairy sheep and goat flocks

Liapi, M.; Leontides, L.; Kostoulas, P.; Botsaris, G.; Iacovou, Y.; Rees, C.; Georgiou, K.; Smith, G. C.; Naseby, D. C. (2011)

We estimated the prevalence of Mycobacterium avium subsp. paratuberculosis (MAP) infected sheep and goats, older than 2 years, reared in the region effectively controlled by the Government of the Republic of Cyprus, in ...

Cell death-inducing effect of novel palladium(II) and platinum(II) complexes on non-small cell lung cancer cells in vitro

Ulukaya, E.; Ari, F.; Dimas, K.; Sarimahmut, M.; Guney, E.; Sakellaridis, N.; Yilmaz, V. T. (2011)

Purpose Treatment for lung cancer is still far from satisfying rates. Therefore, there is a need for novel anticancer agents. For this purpose, novel platinum and palladium complexes {[Pd(sac)(terpy)](sac).4H(2)O (Complex ...

Chronic canine ehrlichiosis (Ehrlichia canis): A retrospective study of 19 natural cases

Mylonakis, M. E.; Koutinas, A. F.; Breitschwerdt, E. B.; Hegarty, B. C.; Billinis, C. D.; Leontides, L. S.; Kontos, V. S. (2004)

Nineteen dogs from Greece with chronic ehrlichiosis were studied. The dogs exhibited bicytopenia or pancytopenia, bone marrow hypoplasia, seroreactivity to Ehrlichia canis ( E. canis) antigens, and had no history of drug ...

DETECTION AND GENETIC CHARACTERIZATION OF PORCINE CIRCOVIRUS 2 ISOLATES FROM THE FIRST CASES OF POSTWEANING MULTISYSTEMIC AND WASTING SYNDROME IN WILD BOARS IN GREECE

Sofia, M.; Billinis, C.; Psychas, V.; Birtsas, P.; Sofianidis, G.; Leontides, L.; Knowles, N.; Spyrou, V. (2008)

In 2002, postweaning multisystemic wasting syndrome (PMWS) was diagnosed in a European female wild boar (Sus scrofa), based on the detection of porcine circovirus 2 (PCV2) DNA in various organs, including the uterus, and ...

Development of GC-MS/MS method with programmable temperature vaporization large volume injection for monitoring of 17 beta-estradiol and 2-methoxyestradiol in plasma

Tsakalof, A. K.; Gkagtzis, D. C.; Koukoulis, G. N.; Hadjichristodoulou, C. S. (2012)

Monitoring of estradiol and its metabolites in biological samples is essential for the accurate diagnosis of a number of endocrine diseases. In this study, a sensitive, precise and specific GC-MS/MS method for the ...

Diagnostic performance of a rapid in-clinic test for the detection of Canine Parvovirus under different storage conditions and vaccination status

Kantere, M. C.; Athanasiou, L. V.; Spyrou, V.; Kyriakis, C. S.; Kontos, V.; Chatzopoulos, D. C.; Tsokana, C. N.; Billinis, C. (2015)

Canine parvovirus (CPV) is one of the most common causes of acute haemorrhagic enteritis in young dogs, while clinical diagnosis is often indecisive. The aim of our study was to evaluate the diagnostic accuracy of an ...

Diagnostic value of anti-cyclic citrullinated peptide antibodies in Greek patients with rheumatoid arthritis

Alexiou, I.; Germenis, A.; Ziogas, A.; Theodoridou, K.; Sakkas, L. I. (2007)

Background: Anti-cyclic citrullinated peptide (anti-CCP) antibodies have been of diagnostic value in Northern European Caucasian patients with rheumatoid arthritis ( RA). In these populations, anti-CCP antibodies are ...

Direct extraction and molecular characterization of enteroviruses genomes from human faecal samples

Bolanaki, E.; Kottaridi, C.; Dedepsidis, E.; Kyriakopoulou, Z.; Pliaka, V.; Pratti, A.; Levidiotou-Stefanou, S.; Markoulatos, P. (2008)

Routine diagnosis of acute flaccid paralysis (AFP) is still based on classical virological procedures. Several enteroviruses serotypes are not easily isolated in cell cultures system used and routinely more than one passage ...

Effects of pesticides on occupationally exposed humans

Piperakis, S. M.; Kontogianni, K.; Piperakis, M. M.; Marcos, R.; Tsilimigaki, S. (2006)

Pesticides are known to contain numerous genotoxic compounds; however, genotoxicity biomonitoring studies of workers occupationally exposed to pesticides have produced variable results. In this study, we employed the Comet ...

Evaluation of cytology in the diagnosis of acute canine monocytic ehrlichiosis (Ehrlichia canis): a comparison between five methods

Mylonakis, M. E.; Koutinas, A. F.; Billinis, C.; Leontides, L. S.; Kontos, V.; Papadopoulos, O.; Rallis, T.; Fytianou, A. (2003)

The purpose of this study was the comparison of the diagnostic sensitivity between buffy coat (BC), peripheral blood (PB), lymph node (LN), bone marrow (BM) and short-term culture (P-D) cytology that has been based on the ...