Πλοήγηση ανά Θέμα "ALLELE"
Αποτελέσματα 1-5 από 5
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The association between apolipoprotein E gene polymorphisms and essential hypertension: a meta-analysis of 45 studies including 13 940 cases and 16 364 controls
(2013)The apolipoprotein E single-nucleotide polymorphisms are among the potential candidate genes that may serve as modulators in susceptibility to essential hypertension. In an effort to clarify earlier inconclusive results, ... -
CYP2D6 polymorphisms and the risk of tardive dyskinesia in schizophrenia: a meta-analysis
(2005)The present study aimed to evaluate whether there is any association between CYP2D6 alleles and susceptibility to tardive dyskinesia in patients with schizophrenia under treatment. A meta-analysis considered case-control ... -
Estimating the mode of inheritance in genetic association studies of qualitative traits based on the degree of dominance index
(2011)Background: The biological justification for the choice of the genetic mode in genetic association studies (GAS) is seldom available. Then, the mode of inheritance is approximated by investigating a number of non-orthogonal ... -
Is catechol-O-methyl transferase 472G/A gene polymorphism a marker associated with alcoholism?
(2011)Objectives The available published evidence from the genetic association studies on the association between alcoholism and catechol-O-methyl transferase 472G/A gene polymorphism have produced inconclusive results. To ... -
The power of generalized odds ratio in assessing association in genetic studies with known mode of inheritance
(2012)The generalized odds ratio (ORG) is a novel model-free approach to test the association in genetic studies by estimating the overall risk effect based on the complete genotype distribution. However, the power of ORG has ...