Πλοήγηση ανά Συγγραφέα "Zacharaki, F."
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Ancestry of the Timorese: Age-related macular degeneration associated genotype and allele sharing among human populations from throughout the world
Morrison, M. A.; Magalhaes, T. R.; Ramke, J.; Smith, S. E.; Ennis, S.; Simpson, C. L.; Portas, L.; Murgia, F.; Ahn, J.; Dardenne, C.; Mayne, K.; Robinson, R.; Morgan, D. J.; Brian, G.; Lee, L.; Woo, S. J.; Zacharaki, F.; Tsironi, E. E.; Miller, J. W.; Kim, I. K.; Park, K. H.; Bailey-Wilson, J. E.; Farrer, L. A.; Stambolian, D.; DeAngelis, M. M. (2015)We observed that the third leading cause of blindness in the world, age-related macular degeneration (AMD), occurs at a very low documented frequency in a population-based cohort from Timor-Leste. Thus, we determined a ... -
European ST80 community-associated methicillin-resistant Staphylococcus aureus orbital cellulitis in a neonate
Tsironi, E. E.; Zacharaki, F.; Grivea, I. N.; Tachmitzi, S. V.; Michoula, A. N.; Vlychou, M.; Petinaki, E.; Syrogiannopoulos, G. A. (2012)Background: Methicillin-resistant Staphylococcus aureus is a serious cause of morbidity and mortality in hospital environment, but also, lately, in the community. This case report is, to our knowledge, the first detailed ... -
FLT1 Genetic Variation Predisposes to Neovascular AMD in Ethnically Diverse Populations and Alters Systemic FLT1 Expression
Owen, L. A.; Morrison, M. A.; Ahn, J.; Woo, S. J.; Sato, H.; Robinson, R.; Morgan, D. J.; Zacharaki, F.; Simeonova, M.; Uehara, H.; Chakravarthy, U.; Hogg, R. E.; Ambati, B. K.; Kotoula, M.; Baehr, W.; Haider, N. B.; Silvestri, G.; Miller, J. W.; Tsironi, E. E.; Farrer, L. A.; Kim, I. K.; Park, K. H.; DeAngelis, M. M. (2014)PURPOSE. Current understanding of the genetic risk factors for age-related macular degeneration (AMD) is not sufficiently predictive of the clinical course. The VEGF pathway is a key therapeutic target for treatment of ... -
Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology
Jun, G.; Nicolaou, M.; Morrison, M. A.; Buros, J.; Morgan, D. J.; Radeke, M. J.; Yonekawa, Y.; Tsironi, E. E.; Kotoula, M. G.; Zacharaki, F.; Mollema, N.; Yuan, Y.; Miller, J. W.; Haider, N. B.; Hageman, G. S.; Kim, I. K.; Schaumberg, D. A.; Farrer, L. A.; DeAngelis, M. M. (2011)ROBO1 is a strong candidate gene for age-related macular degeneration (AMD) based upon its location under a linkage peak on chromosome 3p12, its expression pattern, and its purported function in a pathway that includes ... -
Interleukin-1B and interleukin-1 receptor antagonist gene polymorphisms in Greek multiple sclerosis (MS) patients with bout-onset MS
Aggelakis, K.; Zacharaki, F.; Dardiotis, E.; Xiromerisiou, G.; Tsimourtou, V.; Ralli, S.; Gkaraveli, M.; Bourpoulas, D.; Rodopoulou, P.; Papadimitriou, A.; Hadjigeorgiou, G. (2010)We investigated the association of specific polymorphisms of the interleukin IL-1b (AvaI -511 and TaqI +3,953) and IL-1 receptor antagonist (IL-1RN) (a variable number of tandem repeats; VNTR) genes with both the susceptibility ... -
Intravitreal bevacizumab for photodynamic therapy-induced massive macular detachment in acute central serous chorioretinopathy
Kotoula, M. G.; Zacharaki, F.; Tsironi, E. E. (2012)We present a long followed up case of acute central serous chorioretinopathy (CSC) complicated by a severe visual loss due to massive pigment epithelium detachment of the macula after a full-dose photodynamic therapy (PDT). ... -
Ocular disorders as the prevailing manifestations of antiphospholipid syndrome: A case series
Tsironi, E.; Gatselis, N.; Kotoula, M. G.; Zachou, K.; Pefkianaki, M.; Zacharaki, F.; Chatzoulis, D. Z.; Dalekos, G. N. (2009)Introduction: Antiphospholipid syndrome is an autoimmune disorder characterized by either a history of vascular thrombosis (one or more clinical episodes of arterial, venous, or small vessel thrombosis in any tissue or ... -
Perimetric and retinal nerve fiber layer findings in patients with Parkinson's disease
Tsironi, E. E.; Dastiridou, A.; Katsanos, A.; Dardiotis, E.; Veliki, S.; Patramani, G.; Zacharaki, F.; Ralli, S.; Hadjigeorgiou, G. M. (2012)Background: Visual dysfunction is common in Parkinson's disease (PD). It remains, however, unknown whether it is related to structural alterations of the retina. The aim of this study is to compare visual field (VF) findings ... -
Plasma homocysteine and genetic variants of homocysteine metabolism enzymes in patients from central greece with primary open-angle glaucoma and pseudoexfoliation glaucoma
Zacharaki, F.; Hadjigeorgiou, G. M.; Koliakos, G. G.; Morrison, M. A.; Tsezou, A.; Chatzoulis, D. Z.; Almpanidou, P.; Topouridou, K.; Karabatsas, H. C.; Pefkianaki, M.; DeAngelis, M. M.; Tsironi, E. E. (2014)Background: The purpose of this study was to investigate plasma homocysteine levels and polymorphisms in genes encoding enzymes in the metabolic pathway of homocysteine in association with primary open-angle glaucoma (POAG) ... -
Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration
Morrison, M. A.; Silveira, A. C.; Huynh, N.; Jun, G.; Smith, S. E.; Zacharaki, F.; Sato, H.; Loomis, S.; Andreoli, M. T.; Adams, S. M.; Radeke, M. J.; Jelcick, A. S.; Yuan, Y.; Tsiloulis, A. N.; Chatzoulis, D. Z.; Silvestri, G.; Kotoula, M. G.; Tsironi, E. E.; Hollis, B. W.; Chen, R.; Haider, N. B.; Miller, J. W.; Farrer, L. A.; Hageman, G. S.; Kim, I. K.; Schaumberg, D. A.; DeAngelis, M. M. (2011)Vitamin D has been shown to have anti-angiogenic properties and to play a protective role in several types of cancer, including breast, prostate and cutaneous melanoma. Similarly, vitamin D levels have been shown to be ...