Πλοήγηση ανά Συγγραφέα "Virtanen, A."
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Inhibition of mRNA deadenylation by the nuclear cap binding complex (CBC)
Balatsos, N. A. A.; Nilsson, P.; Mazza, C.; Cusack, S.; Virtanen, A. (2006)Poly(A)-specific ribonuclease (PARN) is a cap-interacting and poly(A)-specific 3′-exoribonuclease. Here we have investigated how the cap binding complex (CBC) affects human PARN activity. We showed that CBC, via its 80-kDa ... -
A multifunctional RNA recognition motif in poly(A)-specific ribonuclease with cap and poly(A) binding properties
Nilsson, P.; Henriksson, N.; Niedzwiecka, A.; Balatsos, N. A. A.; Kokkoris, K.; Eriksson, J.; Virtanen, A. (2007)Poly(A)-specific ribonuclease (PARN) is an oligomeric, processive and cap-interacting 3′ exoribonuclease that efficiently degrades mRNA poly(A) tails. Here we show that the RNA recognition motif (RRM) of PARN harbors both ...