Πλοήγηση ανά Συγγραφέα "Morikis, D."
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Characterization of the interaction between peptides derived from the gp 120/V3 domain of HIV-1 and the amino terminal of the chemokine receptor CCR5 by NMR spectroscopy and light scattering
Rizos, A. K.; Tsikalas, I.; Morikis, D.; Galanakis, P.; Spyroulias, G. A.; Krambovitis, E. (2006)We applied static and dynamic light scattering (DLS) to probe the structural and physicochemical determinants of the interaction between the gp120 V3 domain of the human immunodeficiency virus HIV-1 and the amino terminal ... -
Clustering of HIV-1 Subtypes Based on gp120 V3 Loop electrostatic properties
Lopez de Victoria, A.; Kieslich, C. A.; Rizos, A. K.; Krambovitis, E.; Morikis, D. (2012)Background: The V3 loop of the glycoprotein gp120 of HIV-1 plays an important role in viral entry into cells by utilizing as coreceptor CCR5 or CXCR4, and is implicated in the phenotypic tropisms of HIV viruses. It has ... -
Electrostatic modeling of peptides derived from the V3-loop of HIV-1 gp120: Implications of the interaction with chemokine receptor CCR5
Morikis, D.; Rizos, A. K.; Spandidos, D. A.; Krambovitis, E. (2007)Infection of CD4(+) T cells by macrophage-tropic HIV-1 strains involves interaction of viral gp 120 with the host cell chemokine receptor CCR5. The principle neutralizing determinant (PND) of the V3-loop of the HIV-1 gp120 ... -
NMR Evidence of Charge-Dependent Interaction Between Various PND V3 and CCR5 N-Terminal Peptides
Galanakis, P. A.; Kandias, N. G.; Rizos, A. K.; Morikis, D.; Krambovitis, E.; Spyroulias, G. A. (2009)The third variable (V3) loop is an important region of glycoprotein 120 (gp120) for many biological processes, as it contains the highly conserved GPGR sequence and it represents the binding site for human immunodeficiency ...