Πλοήγηση ανά Συγγραφέα "Lau, J."
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Angiotensin-converting enzyme insertion/deletion gene polymorphic variant as a marker of coronary artery disease - A meta-analysis
Zintzaras, E.; Raman, G.; Kitsios, G.; Lau, J. (2008)Background: Many studies have investigated the association between the angiotensin-converting enzyme (ACE) gene insertion(I)/deletion (D) polymorphic variant and coronary artery disease (CAD). However, the evidence is ... -
APOE gene polymorphisms and response to statin therapy
Zintzaras, E.; Kitsios, G. D.; Triposkiadis, F.; Lau, J.; Raman, G. (2009)Published studies investigating the role of APOE gene on lipid response (total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides) to statin treatment ... -
MTHFR gene polymorphisms and response to chemotherapy in colorectal cancer: a meta-analysis
Zintzaras, E.; Ziogas, D. C.; Kitsios, G. D.; Papathanasiou, A. A.; Lau, J.; Raman, G. (2009)Aims: Pharmacogenetic studies investigating the relationship between MTHFR gene polymorphisms and response to fluorouracil-based chemotherapy in patients with colorectal cancer have produced inconclusive results. In an ... -
Synthesis of genetic association studies for pertinent gene-disease associations requires appropriate methodological and statistical approaches
Zintzaras, E.; Lau, J. (2008)Objective: The aim of the study was to consider statistical and methodological issues affecting the results of meta-analysis of genetic association studies for pertinent gene-disease associations. Although the basic ... -
Trends in meta-analysis of genetic association studies
Zintzaras, E.; Lau, J. (2008)The number of published genetic association studies (GASs) is increasing tremendously due to the availability of mapped single-nucleotide polymorphisms (SNPs) and advances in genotyping technologies. A search in HuGENet ...