Πλοήγηση ανά Συγγραφέα "Boultadakis, A."
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Anesthetic Ketamine Impairs Rats' Recall of Previous Information The Nitric Oxide Synthase Inhibitor N-nitro-L-arginine Methylester Antagonizes This Ketamine-induced Recognition Memory Deficit
Boultadakis, A.; Pitsikas, N. (2011)Background: There is poor experimental evidence concerning the effects of anesthetic doses of the noncompetitive N-methyl-D-aspartate receptor antagonist ketamine on rodents' memory abilities. The current study was designed ... -
Effects of sub-anesthetic doses of ketamine on rats' spatial and non-spatial recognition memory
Pitsikas, N.; Boultadakis, A.; Sakellaridis, N. (2008)There are experimental evidences indicating that the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist ketamine impairs cognition and produces a series of schizophrenia-like symptoms in rodents (hyperactivity, ... -
Effects of the active constituents of Crocus sativus L., crocins, in an animal model of anxiety
Pitsikas, N.; Boultadakis, A.; Georgiadou, G.; Tarantilis, P. A.; Sakellaridis, N. (2008)Crocus sativus L. is a plant cultivated in various parts of the world. Crocins are among the active components of Crocus sativus L. The present study was designed to investigate in the rat whether or not crocins possess ... -
Effects of the nitric oxide synthase inhibitor L-NAME on different memory components as assessed in the object recognition task in the rat
Boultadakis, A.; Georgiadou, G.; Pitsikas, N. (2010)Nitric oxide (NO) is sought to be an intracellular messenger in the central nervous system and its implication in learning and memory is well documented. Compounds that inhibit nitric oxide synthase (NOS), the key synthesizing ... -
Effects of the Nitric Oxide Synthase Inhibitor L-NAME on Recognition and Spatial Memory Deficits Produced by Different NMDA Receptor Antagonists in the Rat
Boultadakis, A.; Pitsikas, N. (2010)There is consistent experimental evidence that noncompetitive antagonists of the N-methyl-D-aspartate (NMDA) receptor, such as ketamine, MK-801, and phencyclidine (PCP), impair cognition and produce psychotomimetic effects ... -
Importance of Body Temperature and Clinical Data in Behavioral and Anesthesia Studies Reply
Boultadakis, A.; Pitsikas, N. (2012) -
The nitric oxide-releasing derivative of ferulic acid NCX 2057 antagonized delay-dependent and scopolamine-induced performance deficits in a recognition memory task in the rat
Boultadakis, A.; Liakos, P.; Pitsikas, N. (2010)Nitric oxide (NO) is considered as an intracellular messenger in the brain. its involvement in learning and memory processes has been proposed. The present study was designed to investigate the effects of the NO-releasing ... -
Pre-training administration of anesthetic ketamine differentially affects rats' spatial and non-spatial recognition memory
Pitsikas, N.; Boultadakis, A. (2009)There is poor experimental evidence concerning the effects of anesthetic doses of the non-competitive NMDA receptor antagonist ketamine on rodents' memory abilities. The present study was designed to investigate a) the ...