Browsing by Author "Befani, C."
Now showing items 1-8 of 8
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The C-terminal Region of HPNAP Activates Neutrophils and Promotes Their Adhesion to Endothelial Cells
Kottakis, F.; Befani, C.; Asiminas, A.; Kontou, M.; Koliakos, G.; Choli-Papadopoulou, T. (2009)Entire Helicobacter Pylori Neutrophil Activated Protein (HPNAP) and its truncated forms NH(2)-terminal region HPNAP(1-57) and C-terminal region HPNAP(58-144) after cloning into pET29c vector, purification and removal of ... -
Cobalt inhibits HIF-2-dependent gene expression by blocking HIF-2 alpha/USF2 interaction in liver cancer cells
Befani, C.; Mylonis, I.; Gkotinakou, I. M.; Georgoulias, P. G.; Hu, C. J.; Simos, G.; Liakos, P. (2014) -
Cobalt stimulates HIF-1-dependent but inhibits HIF-2-dependent gene expression in liver cancer cells
Befani, C.; Mylonis, I.; Gkotinakou, I. M.; Georgoulias, P.; Hu, C. J.; Simos, G.; Liakos, P. (2013)Hypoxia-inducible factors (HIFs) are transcriptional regulators that mediate the cellular response to low oxygen. Although HIF-1 is usually considered as the principal mediator of hypoxic adaptation, several tissues and ... -
Hypoxia causes triglyceride accumulation by HIF-1-mediated stimulation of lipin 1 expression
Mylonis, I.; Sembongi, H.; Befani, C.; Liakos, P.; Siniossoglou, S.; Simos, G. (2012)Adaptation to hypoxia involves hypoxia-inducible transcription factors (HIFs) and requires reprogramming of cellular metabolism that is essential during both physiological and pathological processes. In contrast to the ... -
Low Oxygen Tension Enhances Hepatitis C Virus Replication
Vassilaki, N.; Kalliampakou, K. I.; Kotta-Loizou, I.; Befani, C.; Liakos, P.; Simos, G.; Mentis, A. F.; Kalliaropoulos, A.; Doumba, P. P.; Smirlis, D.; Foka, P.; Bauhofer, O.; Poenisch, M.; Windisch, M. P.; Lee, M. E.; Koskinas, J.; Bartenschlager, R.; Mavromara, P. (2013)Low oxygen tension exerts a significant effect on the replication of several DNA and RNA viruses in cultured cells. In vitro propagation of hepatitis C virus (HCV) has thus far been studied under atmospheric oxygen levels ... -
MgcRacGAP, a cytoskeleton regulator, inhibits HIF-1 transcriptional activity by blocking its dimerization
Lyberopoulou, A.; Mylonis, I.; Papachristos, G.; Sagris, D.; Kalousi, A.; Befani, C.; Liakos, P.; Simos, G.; Georgatsou, E. (2013)Hypoxia inducible factor-1 (HIF-1), a dimeric transcription factor of the bHLH-PAS family, is comprised of HIF-1 alpha, which is inducible by hypoxia and ARNT or HIF-1 beta, which is constitutively expressed. HIF-1 is ... -
Natural agents against neutrophil involvement in H.Pylori induced chronic gastritis
Pendas, S.; Kottakis, F.; Asiminas, A.; Kontou, M.; Befani, C.; Koliakos, G.; Choli-Papadopoulou, T. (2010)Helicobacter pylori infection is one of the widely spread human infections and the major risk for peptic ulcer disease, and gastric cancer and cause for chronic gastric inflammation. The major virulence factors in the ... -
Oxidative stress and inflammatory markers in the exhaled breath condensate of children with OSA
Malakasioti, G.; Alexopoulos, E.; Befani, C.; Tanou, K.; Varlami, V.; Ziogas, D.; Liakos, P.; Gourgoulianis, K.; Kaditis, A. G. (2012)Obstructive sleep apnea (OSA) in children has been associated with systemic inflammation and oxidative stress. Limited evidence indicates that pediatric OSA is associated with oxidative stress and inflammation in the airway. ...