Πλοήγηση ανά Συγγραφέα "Chachami, G."
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MgcRacGAP interacts with HIF-1 alpha and regulates its transcriptional activity
Lyberopoulou, A.; Venieris, E.; Mylonis, I.; Chachami, G.; Pappas, I.; Simos, G.; Bonanou, S.; Georgatsou, E. (2007)HIF-1 alpha is the inducible subunit of the dimeric transcription factor HIF-1 (Hypoxia Inducible Factor 1). It is induced by hypoxia and hypoxia-mimetics in most cell types, as well as non-hypoxic signals such as growth ... -
Oxygen-dependent secretion of a bioactive hepcidin-GFP chimera
Chachami, G.; Lyberopoulou, A.; Kalousi, A.; Paraskeva, E.; Pantopoulos, K.; Simos, G. (2013)Hepcidin, a hepatic hormone, regulates serum iron levels by controlling both intestinal iron absorption and iron release from macrophages. Although transcription of hepcidin is controlled by diverse stimuli, it remains ... -
Regulation of HIF-1alpha activity in airway smooth muscle cells: the role of cobalt and serum
Chachami, G.; Simos, G.; Bonanou, S.; Molyvdas, P. A.; Paraskeva, E. (2005) -
Transport of hypoxia-inducible factor HIF-1 alpha into the nucleus involves importins 4 and 7
Chachami, G.; Paraskeva, E.; Mingot, J. M.; Braliou, G. G.; Gorlich, D.; Simos, G. (2009)Hypoxia-inducible transcription factor 1 (HIF-1) mediates the cellular response to hypoxia. HIF-1 activity is controlled via the synthesis, degradation or intracellular localization of its alpha subunit. HIF-1 alpha contains ...