Browsing by Subject "estradiol"
Now showing items 1-20 of 26
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17-β estradiol attenuates the pro-oxidant activity of corticotropin-releasing hormone in macroendothelial cells
(2019)Corticotropin-releasing hormone, which is the predominant regulator of neuroendocrine responses to stress, attenuates inflammation through stimulation of glucocorticoid release. Enhanced corticotropin-releasing hormone ... -
Alterations in xenobiotic-metabolizing enzyme activities across menstrual cycle in healthy volunteers
(2019)The purpose of the study was to determine whether the in vivo activities of drug-metabolizing enzymes CYP1A2 and CYP2A6, xanthine oxidase (XO), and N-acetyltransferase-2 (NAT2) vary across the menstrual cycle. Forty-two ... -
Anti-apoptotic and antioxidant activities of the mitochondrial estrogen receptor beta in n2a neuroblastoma cells
(2021)Estrogens are steroid hormones that play a crucial role in the regulation of the reproductive and non-reproductive system physiology. Among non-reproductive systems, the nervous system is mainly affected by estrogens due ... -
Changes in pituitary response to gonadotropin releasing hormone following bilateral ovariectomy in women treated with follicle-stimulating hormone
(1996)Superovulation induction in women attenuates the pituitary response to gonadotropin-releasing hormone (GnRH). The aim of this study was to assess the duration of the suppressing activity of the ovaries on the pituitary. ... -
Changes of serum sclerostin and Dickkopf-1 levels during the menstrual cycle. A pilot study
(2016)Studies in postmenopausal women have identified sclerostin as a strong candidate for mediating estrogen effects on the skeleton. The effects of estradiol on sclerostin and Dickkopf-1 in younger women remain unclear. The ... -
The effect of a GnRH antagonist on follicle maturation in normal women
(2019)Research question: Ganirelix is a gonadotrophin-releasing hormone (GnRH) antagonist used for the prevention of premature LH surge during ovarian stimulation. What is the impact of ganirelix on follicle maturation in normal ... -
Effect of adiponectin on estradiol and progesterone secretion from human luteinized granulosa cells in vitro
(2021)Ιnformation on the role of adiponectin in human ovarian steroidogenesis is limited. The present study aimed to investigate the effect of different doses of adiponectin on the secretion of estradiol and progesterone by human ... -
Effect of exogenous estrogens and progestogens on the course of migraine during reproductive age: A consensus statement by the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESCRH)
(2018)We systematically reviewed data about the effect of exogenous estrogens and progestogens on the course of migraine during reproductive age. Thereafter a consensus procedure among international experts was undertaken to ... -
The Effect of Metformin on the Endometrium of Women with Polycystic Ovary Syndrome
(2019)Objectives: To investigate the effect of metformin on endometrial receptivity in women with polycystic ovary syndrome (PCOS). Methods: Twenty volunteer women with polycystic ovaries and oligomenorrhea were prospectively ... -
Effect of mifepristone on folliculogenesis in women treated with recombinant FSH
(1997)Objective: To study the mechanism through which mifepristone interrupts folliculogenesis. Design: Normally ovulating women undergoing donor intrauterine insemination (IUI) treatment were investigated during two menstrual ... -
Effect of resistin on estradiol and progesterone secretion from human luteinized granulosa cells in culture
(2019)Information on the role of resistin on steroidogenesis is limited to animal studies. The aim of this study was to investigate the effect of various doses of resistin on estradiol and progesterone secretion from human ... -
Endocrine resistance and epigenetic reprogramming in estrogen receptor positive breast cancer
(2021)Despite the enormous advances during the last three decades, breast cancer continues to be the most frequent type of cancer as well as one of the most frequent cancer-related causes of death in women. Therapeutic management ... -
Evidence of differential control of FSH and LH responses to GnRH by ovarian steroids in the luteal phase of the cycle
(2002)BACKGROUND: It is known that during the follicular phase of the cycle, estradiol sensitizes the pituitary to GnRH. The aim of this study was to determine the role of ovarian steroids in the control of GnRH-induced gonadotrophin ... -
From menarche to regular menstruation - Endocrinological background
(2006)Marked changes in hormone secretion occur from childhood to adulthood. Prior to puberty gonadotropin-releasing hormone (GnRH) secretion is markedly suppressed. At the onset of puberty, the hypothalamic gonadostat is ... -
Inhibitory Effect of Submaximal Doses of Ghrelin on Gonadotropin Secretion in Women
(2014)The effect of ghrelin on gonadotropin secretion has been equivocal. Recent data have shown an inhibitory effect of repeated injections of ghrelin on nocturnal LH and FSH secretion in women. The aim of this study was to ... -
Initiation of GnRH antagonist on Day 1 of stimulation as compared to the long agonist protocol in PCOS patients. A randomized controlled trial: effect on hormonal levels and follicular development
(2007)BACKGROUND: The optimal time for GnRH antagonist initiation is still debatable. The purpose of the current randomized controlled trial is to provide endocrine and follicular data during ovarian stimulation for IVF in ... -
Leptin concentrations in normal women following bilateral ovariectomy
(1999)To study the relationships between gonadal steroids and leptin, 20 women with normal cycles were investigated during the postoperative period following a laparotomy. Fourteen women underwent bilateral ovariectomy plus total ... -
Physical activity may be a potent regulator of bone turnover biomarkers in healthy girls during preadolescence
(2017)This study investigated the effects of different levels of habitual physical activity (PA) assessed by pedometry on bone turnover markers of preadolescent girls according to a cross-sectional experimental design. Sixty ... -
Rapid effects of 17β-estradiol and progesterone on sheep visceral and parietal pleurae via a nitric oxide pathway
(2002)We investigated the effects of 17β-estradiol and progesterone on transepithelial electrical resistance (R TE) in sheep visceral and parietal pleurae. Specimens of intact pleurae from adult female sheep were used. The samples ... -
Regulation of aromatase expression by hormones, drugs pesticides and environmental pollutants in canine mammary CMT-U27 cells
(2010)Aromatase, the enzyme that coverts testosterone to 17β-estradiol, has attracted attention lately because of its involvement in some forms of breast cancer in women. Studies are now undergoing on a variety of species to ...