Πλοήγηση ανά Θέμα "nitroprusside sodium"
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Acute and repeated exposure with the nitric oxide (NO) donor sodium nitroprusside (SNP) differentially modulate responses in a rat model of anxiety
(2017)The nitric oxide (NO) donor sodium nitroprusside (SNP) actually is under investigation for the treatment of schizophrenia. That anxiety disorders are noted to occur commonly in schizophrenia patients is known. Contradictory ... -
Effects of low doses of different nitric oxide (NO) donors in rat models of obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD)
(2022)Several lines of evidence suggest that the intra- and inter-cellular messenger nitric oxide (NO) is critically involved in anxiety. Contrasting findings are reported, however, regarding the effects of NO donors in preclinical ... -
Hyponatremia in Acute Stroke Patients: Pathophysiology, Clinical Significance, and Management Options
(2020)Background: Hyponatremia is frequent in acute stroke patients, and it is associated with worse outcomes and increased mortality. Summary: Nonstroke-related causes of hyponatremia include patients' comorbidities and concomitant ... -
The nitric oxide (No) donor sodium nitroprusside (snp) and its potential for the schizophrenia therapy: Lights and shadows
(2021)Schizophrenia is a severe psychiatric disorder affecting up to 1% of the worldwide popula-tion. Available therapy presents different limits comprising lack of efficiency in attenuating negative symptoms and cognitive ... -
The nitric oxide donor sodium nitroprusside attenuates recognition memory deficits and social withdrawal produced by the NMDA receptor antagonist ketamine and induces anxiolytic-like behaviour in rats
(2016)Rationale: Experimental evidence indicates that the non-competitive N-methyl-d-aspartate (NMDA) receptor antagonist ketamine impairs cognition and can mimic certain aspects of positive and negative symptoms of schizophrenia ... -
Personalized physiology-guided resuscitation in highly monitored patients with cardiac arrest—the PERSEUS resuscitation protocol
(2019)Resuscitation guidelines remain uniform across all cardiac arrest patients, focusing on the delivery of chest compressions to a standardized rate and depth and algorithmic vasopressor dosing. However, individualizing ... -
Posterior reversible encephalopathy in a GT1a positive oculopharyngeal variant of Guillain-Barré syndrome: A case-report and review of the literature
(2020)Guillain-Barre syndrome (GBS) is the most common cause of acute flaccid paralysis and its incidence increases with age, although all age groups can be affected. The cranial subtypes of GBS account for approximately 5% of ... -
Repeated but not acute exposure with a low dose range of the nitric oxide (NO) donor sodium nitroprusside (SNP) induces anxiolytic-like behaviour in a dose-independent manner in two different rat models of anxiety
(2020)Sodium nitroprusside (SNP) is a nitric oxide (NO) donor which actually is under assessment as a potential candidate for the treatment of schizophrenia. It is well documented that anxiety symptoms are a prominent future in ... -
The role of nitric oxide donors in schizophrenia: Basic studies and clinical applications
(2015)Schizophrenia is a complex and chronic mental health disease that affects nearly 1% of the population worldwide. While the current antipsychotic medications have profoundly impacted the treatment of schizophrenia over the ... -
The role of nitric oxide in the pathophysiology of bronchial asthma
(1998)OBJECTIVE: To study in vitro the role of nitric oxide (NO), in the pathophysiology of asthma observing the effections of a NO-donor such as sodium nitroprusside, a calcium (Ca) channel inhibitor nifedipine or neurotransmitter ...