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Hyphenated Extraction of Valuable Compounds from Aesculus carnea: Ultrasound Extraction with Pulsed Electric Field Pretreatment
(2022)Wood-related procedures, such as lumberjacking and pruning, inevitably result in big piles of leaves, which are considered a major by-product. Extracting valuable compounds from natural by-products is an ongoing trend. In ... -
Hyponatremia as a marker of complicated appendicitis: A systematic review
(2020)Background: Acute appendicitis, the most common cause of acute surgical abdomen, is associated with intra-abdominal complications, such as perforation, that increase morbidity and mortality. Early and accurate preoperative ... -
Hyponatremia in Acute Stroke Patients: Pathophysiology, Clinical Significance, and Management Options
(2020)Background: Hyponatremia is frequent in acute stroke patients, and it is associated with worse outcomes and increased mortality. Summary: Nonstroke-related causes of hyponatremia include patients' comorbidities and concomitant ... -
Hypospadias in offspring is associated with chronic exposure of parents to organophosphate and organochlorine pesticides
(2014)We have currently evaluated the possible association between hypospadias and exposure to organophosphorus (OP) and organochlorine (OC) pesticides. For this purpose, we measured the dialkyl phosphate metabolites of ... -
Hypothalamic inflammation as a potential pathophysiologic basis for the heterogeneity of clinical, hormonal, and metabolic presentation in pcos
(2021)Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among women of reproductive age. It is a heterogeneous condition characterized by reproductive, endocrine, metabolic, and psychiatric abnormalities. ... -
Hypoventilation disproportionate to OSAS severity in children with Prader-Willi syndrome
(2019)Objective To test the hypothesis that children with Prader-Willi syndrome (PWS) and obstructive sleep apnoea syndrome (OSAS) have hypercapnia for higher proportion of total sleep time (TST) than non-syndromic children with ... -
Hypoxia causes triglyceride accumulation by HIF-1-mediated stimulation of lipin 1 expression
(2012)Adaptation to hypoxia involves hypoxia-inducible transcription factors (HIFs) and requires reprogramming of cellular metabolism that is essential during both physiological and pathological processes. In contrast to the ... -
Hypoxia inducible factor (HIF-1a and HIF-2a) expression in early esophageal cancer and response to photodynamic therapy and radiotherapy
(2001)Hypoxia inducible factor 1a and 2a (HIF-1a and HIF-2a) are key proteins regulating cellular response to hypoxia, Because the efficacy of photodynamic therapy (PDT) is dependent on the presence of oxygen, the assessment of ... -
Hypoxia Inducible Factor-1alpha and Vascular Endothelial Growth Factor in Biopsies of Small Cell Lung Carcinoma
(2009)Neoangiogenesis has been documented in small cell lung carcinoma (SCLC). In addition, antiangiogenic therapies are being tested in clinical trials that involve SCLC. However, study of the underlying mechanisms has been ... -
Hypoxia upregulates integrin gene expression in microvascular endothelial cells and promotes their migration and capillary-like tube formation
(2017)Tissue hypoxia affects gene expression through the hypoxia-inducible transcription factors, HIF-1 and HIF-2, in both physiological and pathological angiogenesis. Angiogenesis is a complex response of endothelial cells ... -
Hypoxia upregulates the expression of the O-linked N-acetylglucosamine containing epitope H in human ependymal cells
(2011)Epitope H contains an O-linked N-acetylglucosamine (O-GlcNAc) residue in a specific conformation and/or environment recognized by mouse IgM monoclonal antibody H (mabH). Epitope H is present in several types of cells and ... -
Hypoxia-induced changes in plasma micro-RNAs correlate with pulmonary artery pressure at high altitude
(2018)In vitro and animal studies revealed micro-RNAs (miRs) to be involved in modulation of hypoxia-induced pulmonary hypertension (HPH). However, knowledge of circulating miRs in humans in the context of HPH is very limited. ... -
Hypoxia-induced Changes in SUMO Conjugation Affect Transcriptional Regulation under Low Oxygen
(2019)Hypoxia occurs in pathological conditions, such as cancer, as a result of the imbalance between oxygen supply and consumption by proliferating cells. HIFs are critical molecular mediators of the physiological response to ... -
Hypoxia-induced collagen crosslinking as a mechanism for enhancing mechanical properties of engineered articular cartilage
(2013)Objective: The focus of tissue engineering of neocartilage has traditionally been on enhancing extracellular matrix and thus biomechanical properties. Emphasis has been placed on the enhancement of collagen type and quantity, ... -
Hypoxia-inducible factor 1-alpha and vascular endothelial growth factor in cartilage tumors
(2019)Neoangiogenesis has been demonstrated in chondrosarcoma. Anti-angiogenic therapies are being tested in clinical trials for chondrosarcomas. Studies of the underlying mechanisms have been performed almost exclusively in ... -
Hypoxia-inducible factor-1 alpha (HIF-1 alpha) expression in placentae of women with iron deficiency anemia and beta-thalassemia trait
(2015)Objective: To investigate hypoxia-inducible factor-1 alpha (HIF-1 alpha) expression in placentae of women with iron-deficiency anemia and beta-thalassemia trait and to correlate the results with hematological parameters ... -
Hypoxia-Inducible Factor-2-Altered Urothelial Carcinoma: Clinical and Genomic Features
(2022)Background: Hypoxia is recognized as a key feature of cancer growth and is involved in various cellular processes, including proliferation, angiogenesis, and immune surveillance. Besides hypoxia-inducible factor 1-alpha ... -
Hypoxia-inducible factors and the regulation of lipid metabolism
(2019)Oxygen deprivation or hypoxia characterizes a number of serious pathological conditions and elicits a number of adaptive changes that are mainly mediated at the transcriptional level by the family of hypoxia-inducible ... -
The hysteretic effects on the real exchange rates
(2002)In this paper we investigate the dynamics developed from the exchange rate relative price relationship using a hysteresis framework. The rationale for such hysteretic effects is in terms of firms' unresponsiveness to the ... -
HΜGB1/sRAGE levels differ significantly between transudates and exudates
(2021)High mobility group box 1(HMGB1) protein operates as an alarmin with multiple roles in immunity and cell homeostasis. It is highly expressed in epithelial barrier sites and acts via the binding to the receptor for advanced ...