• Early recurrence and major bleeding in patients with acute ischemic stroke and atrial fibrillation treated with Non-Vitamin-K oral anticoagulants (RAF-NOACs) Study 

      Paciaroni M., Agnelli G., Falocci N., Tsivgoulis G., Vadikolias K., Liantinioti C., Chondrogianni M., Bovi P., Carletti M., Cappellari M., Zedde M., Ntaios G., Karagkiozi E., Athanasakis G., Makaritsis K., Silvestrelli G., Lanari A., Ciccone A., Putaala J., Tomppo L., Tatlisumak T., Abdul-Rahim A.H., Lees K.R., Alberti A., Venti M., Acciarresi M., D'Amore C., Becattini C., Mosconi M.G., Cimini L.A., Soloperto R., Masotti L., Vannucchi V., Lorenzini G., Tassi R., Guideri F., Acampa M., Martini G., Sohn S.-I., Marcheselli S., Mumoli N., De Lodovici M.L., Bono G., Furie K.L., Tadi P., Yaghi S., Toni D., Letteri F., Tassinari T., Kargiotis O., Lotti E.M., Flomin Y., Mancuso M., Maccarrone M., Giannini N., Bandini F., Pezzini A., Poli L., Padovani A., Scoditti U., Denti L., Consoli D., Galati F., Sacco S., Carolei A., Tiseo C., Gourbali V., Orlandi G., Giuntini M., Chiti A., Giorli E., Gialdini G., Corea F., Ageno W., Bellesini M., Colombo G., Monaco S., Baronello M.M., Karapanayiotides T., Caso V. (2017)
      Background--The optimal timing to administer non-vitamin K oral anticoagulants (NOACs) in patients with acute ischemic stroke and atrial fibrillation is unclear. This prospective observational multicenter study evaluated ...
    • Effectiveness and safety of intracranial events associated with the use of direct oral anticoagulants for atrial fibrillation: A systematic review and meta-analysis of 92 studies 

      Archontakis-Barakakis P., Li W., Kalaitzoglou D., Tzelves L., Manolopoulos A., Giannopoulos S., Giamouzis G., Giannakoulas G., Batsidis A., Palaiodimos L., Ntaios G., Lip G.Y.H., Kokkinidis D.G. (2022)
      Aims: Observational studies have investigated the effectiveness and safety of direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) used in nonvalvular atrial fibrillation. We performed a systematic review ...
    • Embolic Stroke of Undetermined Source and Detection of Atrial Fibrillation on Follow-Up: How Much Causality Is There? 

      Ntaios G., Papavasileiou V., Lip G.Y.H., Milionis H., Makaritsis K., Vemmou A., Koroboki E., Manios E., Spengos K., Michel P., Vemmos K. (2016)
      Background There is increasing debate whether atrial fibrillation (AF) episodes during follow-up in patients with embolic stroke of undetermined source (ESUS) are causally associated with the event. AF-related strokes are ...
    • Embolic Stroke of Undetermined Source and Patent Foramen Ovale: Risk of Paradoxical Embolism Score Validation and Atrial Fibrillation Prediction 

      Strambo D., Sirimarco G., Nannoni S., Perlepe K., Ntaios G., Vemmos K., Michel P. (2021)
      Background and Purpose: The Risk of Paradoxical Embolism (RoPE) score stratifies patients with stroke according to the probability of having a patent foramen ovale (PFO), which (through Bayes theorem and simple assumptions) ...
    • Estimation of the economic burden of atrial fibrillation-related stroke in Greece 

      Vemmos K., Boubouchairopoulou N., Stafylas P., Vitsou E., Giannakoulas G., Ntaios G., Milionis H., Hahalis G., Parthenakis F., Tsioufis K. (2022)
      Background: Stroke is aleading cause of death and disability, with atrial fibrillation (AF) being among key risk factors and AF-related stroke inflicting significant burden on healthcare systems and society. The present ...
    • External Performance of the HAVOC Score for the Prediction of New Incident Atrial Fibrillation 

      Ntaios G., Perlepe K., Lambrou D., Sirimarco G., Strambo D., Eskandari A., Karagkiozi E., Vemmou A., Koroboki E., Manios E., Makaritsis K., Vemmos K., Michel P. (2020)
      Background and Purpose-The HAVOC score (hypertension, age, valvular heart disease, peripheral vascular disease, obesity, congestive heart failure, coronary artery disease) was proposed for the prediction of atrial fibrillation ...
    • Hemorrhagic transformation in patients with acute ischemic stroke and atrial fibrillation: Time to initiation of oral anticoagulant therapy and outcomes 

      Paciaroni M., Bandini F., Agnelli G., Tsivgoulis G., Yaghi S., Furie K.L., Tadi P., Becattini C., Zedde M., Abdul-Rahim A.H., Lees K.R., Alberti A., Venti M., Acciarresi M., D’Amore C., Mosconi M.G., Cimini L.A., Altavilla R., Volpi G., Bovi P., Carletti M., Rigatelli A., Cappellari M., Putaala J., Tomppo L., Tatlisumak T., Marcheselli S., Pezzini A., Poli L., Padovani A., Masotti L., Vannucchi V., Sohn S.-I., Lorenzini G., Tassi R., Guideri F., Acampa M., Martini G., Ntaios G., Athanasakis G., Makaritsis K., Karagkiozi E., Vadikolias K., Liantinioti C., Chondrogianni M., Mumoli N., Consoli D., Galati F., Sacco S., Carolei A., Tiseo C., Corea F., Ageno W., Bellesini M., Colombo G., Silvestrelli G., Ciccone A., Lanari A., Scoditti U., Denti L., Mancuso M., Maccarrone M., Ulivi L., Orlandi G., Giannini N., Gialdini G., Tassinari T., De Lodovici M.L., Bono G., Rueckert C., Baldi A., D'Anna S., Toni D., Letteri F., Giuntini M., Lotti E.M., Flomin Y., Pieroni A., Kargiotis O., Karapanayiotides T., Monaco S., Baronello M.M., Csiba L., Szabó L., Chiti A., Giorli E., Del Sette M., Imberti D., Zabzuni D., Doronin B., Volodina V., Michel P., Vanacker P., Barlinn K., Pallesen L.-P., Barlinn J., Deleu D., Melikyan G., Ibrahim F., Akhtar N., Gourbali V., Caso V. (2018)
      Background—In patients with acute ischemic stroke and atrial fibrillation, early anticoagulation prevents ischemic recurrence but with the risk of hemorrhagic transformation (HT). The aims of this study were to evaluate ...
    • Identification of patients with embolic stroke of undetermined source and low risk of new incident atrial fibrillation: The AF-ESUS score 

      Ntaios G., Perlepe K., Lambrou D., Sirimarco G., Strambo D., Eskandari A., Karagkiozi E., Vemmou A., Korompoki E., Manios E., Makaritsis K., Vemmos K., Michel P. (2021)
      Background and aims: Only a minority of patients with Embolic Stroke of Undetermined Source (ESUS) receive prolonged cardiac monitoring despite current recommendations. The identification of ESUS patients who have low ...
    • Integrated care for optimizing the management of stroke and associated heart disease: a position paper of the European Society of Cardiology Council on Stroke 

      Lip G.Y.H., Lane D.A., Lenarczyk R., Boriani G., Doehner W., Benjamin L.A., Fisher M., Lowe D., Sacco R.L., Schnabel R., Watkins C., Ntaios G., Potpara T. (2022)
      The management of patients with stroke is often multidisciplinary, involving various specialties and healthcare professionals. Given the common shared risk factors for stroke and cardiovascular disease, input may also be ...
    • Left atrial diameter thresholds and new incident atrial fibrillation in embolic stroke of undetermined source 

      Perlepe K., Sirimarco G., Strambo D., Eskandari A., Karagkiozi E., Vemmou A., Koroboki E., Manios E., Makaritsis K., Vemmos K., Michel P., Ntaios G. (2020)
      Background and purpose: We analyzed consecutive patients with embolic stroke of undetermined source (ESUS) from three prospective stroke registries to compare the prognostic performance of different LAD thresholds for the ...
    • Lipids and atrial fibrillation: New insights into a paradox 

      Sagris D., Harrison S.L., Lip G.Y.H. (2022)
      [No abstract available]
    • Long-Term Cardiac Monitoring After Embolic Stroke of Undetermined Source: Search Longer, Look Harder 

      Sagris D., Harrison S.L., Buckley B.J.R., Ntaios G., Lip G.Y.H. (2022)
      Embolic stroke of undetermined source (ESUS) represents a heterogeneous subgroup of patients with cryptogenic stroke, in which despite an extensive diagnostic workup the cause of stroke remains uncertain. Identifying covert ...
    • The management of atrial fibrillation in heart failure: an expert panel consensus 

      Farmakis D., Chrysohoou C., Giamouzis G., Giannakoulas G., Hamilos M., Naka K., Tzeis S., Xydonas S., Karavidas A., Parissis J. (2021)
      Heart failure (HF) and atrial fibrillation (AF) often coexist, being closely interrelated as the one increases the prevalence and incidence and worsens the prognosis of the other. Their frequent coexistence raises several ...
    • Measurement of Midregional Pro-Atrial Natriuretic Peptide to Discover Atrial Fibrillation in Patients With Ischemic Stroke 

      Schweizer J., Arnold M., König I.R., Bicvic A., Westphal L.P., Schütz V., Inauen C., Scherrer N., Luft A., Galovic M., Ferreira Atuesta C., Pokorny T., Arnold M., Fischer U., Bonati L.H., De Marchis G.M., Kahles T., Nedeltchev K., Cereda C.W., Kägi G., Bustamante A., Montaner J., Ntaios G., Sagris D., Foerch C., Spanaus K., von Eckardstein A., Katan M. (2022)
      Background: Midregional pro-atrial natriuretic peptide (MR-proANP) is a promising biomarker to differentiate the underlying etiology of acute ischemic stroke (AIS). Objectives: This study aimed to determine the role of ...
    • Non-Vitamin K Antagonist Oral Anticoagulants in Coronary Artery Disease 

      Al Said S., Ellscheid M., Beltsios E.T., Frey N. (2022)
      The prevention of atherothrombotic events is the primary goal in the treatment of patients with arteriosclerotic disorders. Despite recent improvements in the management of coronary artery disease (CAD) with revascularization ...
    • Non-vitamin-K oral anticoagulants (NOACs) for the prevention of secondary stroke 

      Diener H.-C., Ntaios G., O’Donnell M., Easton J.D. (2018)
      Introduction: In patients with atrial fibrillation (AF), oral anticoagulation with vitamin K antagonists (VKA) (warfarin, phenprocoumon) is effective both for primary and secondary stroke prevention with a 60–70% relative ...
    • Nonvitamin-K-antagonist oral anticoagulants versus warfarin in patients with atrial fibrillation and previous stroke or transient ischemic attack: An updated systematic review and meta-analysis of randomized controlled trials 

      Ntaios G., Papavasileiou V., Diener H.-C., Makaritsis K., Michel P. (2017)
      Background: In a previous systematic review and meta-analysis, we assessed the efficacy and safety of nonvitamin-K antagonist oral anticoagulants versus warfarin in patients with atrial fibrillation and stroke or transient ...
    • Prediction of Early Recurrent Thromboembolic Event and Major Bleeding in Patients with Acute Stroke and Atrial Fibrillation by a Risk Stratification Schema: The ALESSA Score Study 

      Paciaroni M., Agnelli G., Caso V., Tsivgoulis G., Furie K.L., Tadi P., Becattini C., Falocci N., Zedde M., Abdul-Rahim A.H., Lees K.R., Alberti A., Venti M., Acciarresi M., D'Amore C., Mosconi M.G., Cimini L.A., Procopio A., Bovi P., Carletti M., Rigatelli A., Cappellari M., Putaala J., Tomppo L., Tatlisumak T., Bandini F., Marcheselli S., Pezzini A., Poli L., Padovani A., Masotti L., Vannucchi V., Sohn S.-I., Lorenzini G., Tassi R., Guideri F., Acampa M., Martini G., Ntaios G., Karagkiozi E., Athanasakis G., Makaritsis K., Vadikolias K., Liantinioti C., Chondrogianni M., Mumoli N., Consoli D., Galati F., Sacco S., Carolei A., Tiseo C., Corea F., Ageno W., Bellesini M., Colombo G., Silvestrelli G., Ciccone A., Scoditti U., Denti L., Mancuso M., Maccarrone M., Orlandi G., Giannini N., Gialdini G., Tassinari T., De Lodovici M.L., Bono G., Rueckert C., Baldi A., D'Anna S., Toni D., Letteri F., Giuntini M., Lotti E.M., Flomin Y., Pieroni A., Kargiotis O., Karapanayiotides T., Monaco S., Baronello M.M., Csiba L., Szabó L., Chiti A., Giorli E., Del Sette M., Imberti D., Zabzuni D., Doronin B., Volodina V., Michel P., Vanacker P., Barlinn K., Pallesen L.-P., Kepplinger J., Bodechtel U., Gerber J., Deleu D., Melikyan G., Ibrahim F., Akhtar N., Gourbali V., Yaghi S. (2017)
      Background and Purposes - This study was designed to derive and validate a score to predict early ischemic events and major bleedings after an acute ischemic stroke in patients with atrial fibrillation. Methods - The ...
    • Prolonged Cardiac Monitoring and Stroke Recurrence: A Meta-analysis 

      Tsivgoulis G., Triantafyllou S., Palaiodimou L., Grory B.M., Deftereos S., Köhrmann M., Dilaveris P., Ricci B., Tsioufis K., Cutting S., Magiorkinis G., Krogias C., Schellinger P.D., Dardiotis E., Rodriguez-Campello A., Cuadrado-Godia E., Aguiar De Sousa D., Sharma M., Gladstone D.J., Sanna T., Wachter R., Furie K.L., Alexandrov A.V., Yaghi S., Katsanos A.H. (2022)
      Background and ObjectivesProlonged poststroke cardiac rhythm monitoring (PCM) reveals a substantial proportion of patients with ischemic stroke (IS) with atrial fibrillation (AF) not detected by conventional rhythm monitoring ...