• The role of leptin in the respiratory system: an overview 

      Malli, F.; Papaioannou, A. I.; Gourgoulianis, K. I.; Daniil, Z. (2010)
      Since its cloning in 1994, leptin has emerged in the literature as a pleiotropic hormone whose actions extend from immune system homeostasis to reproduction and angiogenesis. Recent investigations have identified the lung ...
    • Secondhand smoke exposure induces acutely airway acidification and oxidative stress 

      Kostikas, K.; Minas, M.; Nikolaou, E.; Papaioannou, A. I.; Liakos, P.; Gougoura, S.; Gourgoulianis, K. I.; Dinas, P. C.; Metsios, G. S.; Jamurtas, A. Z.; Flouris, A. D.; Koutedakis, Y. (2013)
      Previous studies have shown that secondhand smoke induces lung function impairment and increases proinflammatory cytokines. The aim of the present study was to evaluate the acute effects of secondhand smoke on airway ...
    • Serum levels of oxidative stress as a marker of disease severity in idiopathic pulmonary fibrosis 

      Daniil, Z. D.; Papageorgiou, E.; Koutsokera, A.; Kostikas, K.; Kiropoulos, T.; Papaioannou, A. I.; Gourgoulianis, K. I. (2008)
      Background: Idiopathic Pulmonary fibrosis (IPF) is a fatal illness characterized by progressive fibrosis resulting in severe dyspnea and impairment Of lung function. Although the mechanisms by which lung fibrosis develops ...
    • Serum vascular endothelial growth factor is related to systemic oxidative stress in patients with lung cancer 

      Katsabeki-Katsafli, A.; Kerenidi, T.; Kostikas, K.; Dalaveris, E.; Kiropoulos, T. S.; Gogou, E.; Papaioannou, A. I.; Gourgoulianis, K. I. (2008)
      Vascular endothelial growth factor (VEGF) is known to play crucial rote in tumour angiogenesis. It is demonstrated that VEGF can be up-regulated by oxidative stress. The aim of this study was to determine the serum VEGF ...
    • Serum VEGF levels are related to the presence of pulmonary arterial hypertension in systemic sclerosis 

      Papaioannou, A. I.; Zakynthinos, E.; Kostikas, K.; Kiropoulos, T.; Koutsokera, A.; Ziogas, A.; Koutroumpas, A.; Sakkas, L.; Gourgoulianis, K. I.; Daniil, Z. D. (2009)
      Background: The association between systemic sclerosis and pulmonary arterial hypertension (PAH) is well recognized. Vascular endothelial growth factor (VEGF) has been reported to play an important role in pulmonary ...
    • Sex discrepancies in COPD patients and burden of the disease in females: a nationwide study in Greece (Greek Obstructive Lung Disease Epidemiology and health ecoNomics: GOLDEN study) 

      Papaioannou, A. I.; Bania, E.; Alexopoulos, E. C.; Mitsiki, E.; Malli, F.; Gourgoulianis, K. I. (2014)
      Background: The prevalence of chronic obstructive pulmonary disease (COPD) in females appears to be increasing. Recent studies have revealed that the percentage of women with COPD in Greece is approximately 12.5%. Aims: ...
    • Spirometric values in Gypsy (Roma) children 

      Kaditis, A. G.; Gourgoulianis, K.; Tsoutsou, P.; Papaioannou, A. I.; Fotiadou, A.; Messini, C.; Samaras, K.; Piperi, M.; Gissaki, D.; Zintzaras, E.; Molyvdas, A. P. (2008)
      Values of spirometry indices vary among subjects of similar age, gender and somatometrics but of different ethnic origins. Low socioeconomic status in childhood is inversely related to lung growth. The aim of this investigation ...
    • Statins and outcome after hospitalization for COPD exacerbation: A prospective study 

      Bartziokas, K.; Papaioannou, A. I.; Minas, M.; Kostikas, K.; Banya, W.; Daniil, Z. D.; Haniotou, A.; Gourgoulianis, K. I. (2011)
      Background: Retrospective studies have shown that the use of statins is associated with reduced mortality and decreased hospitalizations from COPD, but data from prospective studies are lacking. Methods: We followed-up ...
    • Systemic and airway inflammation and the presence of emphysema in patients with COPD 

      Papaioannou, A. I.; Mazioti, A.; Kiropoulos, T.; Tsilioni, I.; Koutsokera, A.; Tanou, K.; Nikoulis, D. J.; Georgoulias, P.; Zakynthinos, E.; Gourgoulianis, K. I.; Kostikas, K. (2010)
      The aim of this study was to determine the impact of HRCT-confirmed emphysema on biomarkers evaluating airway and systemic inflammation in COPD patients. Forty-nine consecutive male COPD outpatients with stable COPD were ...
    • Systemic oxidative stress in patients with pulmonary sarcoidosis 

      Koutsokera, A.; Papaioannou, A. I.; Malli, F.; Kiropoulos, T. S.; Katsabeki, A.; Kerenidi, T.; Gourgoulianis, K. I.; Daniil, Z. D. (2009)
      Background: A local redox imbalance has been reported in pulmonary sarcoidosis. However so far no, study has described a systemic redox imbalance in this context. The aim of the present study was to evaluate the systemic ...