Myomectomy during pregnancy: A systematic review
Datum
2020Language
en
Schlagwort
Zusammenfassung
Objective: Uterine fibroids affect 2–10 % of pregnant women. Although usually asymptomatic, they may be associated with pregnancy complications. Myomectomy is preferably avoided antenatally, however, it has been reported in symptomatic cases that did not respond to conservative management. The aim of this study was to summarize the published literature and present the reported outcomes and associated risks of this procedure. Study Design: A systematic research of the literature was conducted in PubMed/MEDLINE, Scopus and the Cochrane Library, including case reports and case series. An effort was made to numerically analyse all parameters included in the case reports. Results: Overall, 54 relevant articles were identified, including 97 patients. The median gestational age at diagnosis was 13 (range 6–26) weeks, while the median age at myomectomy was 16 (range 6–26) weeks. Abdominal pain, not responding to medical treatment was the most common indication for surgery. The median number of fibroids removed per patient was one (range 1–5). Most of them were subserous pedunculated or subserous and fundal. Laparotomy (78.4 %) was the principal surgical approach, however, laparoscopic and vaginal operations were also reported. The median duration of surgery was 53 (range 20–150) min. The histopathology revealed necrosis and degeneration as the main findings of removed fibroids. The pregnancy outcome was favourable in most of the cases, with few complications reported. Conclusion: Based on the limited published data, myomectomy during pregnancy appears as a safe procedure in cases of symptomatic uterine fibroids not responding to conservative management and therefore it may be considered, following appropriate counselling regarding the associated risks. © 2020 Elsevier B.V.
Collections
Verwandte Dokumente
Anzeige der Dokumente mit ähnlichem Titel, Autor, Urheber und Thema.
-
Effectors of Pregorexia and Emesis among Pregnant Women: A Pilot Study
Gerontidis A., Grammatikopoulou M.G., Tzimos C., Gkiouras K., Taousani E., Athanasiadis L., Goulis D.G. (2022)During pregnancy, women tend to improve their lifestyle habits and refine their dietary intake. Quite often, however, these dietary improvements take an unhealthy turn, with orthorexia nervosa (ON) practices being apparent. ... -
Placental expression of PAPPA, PAPPA-2 and PLAC-1 in pregnacies is associated with FGR
Sifakis S., Androutsopoulos V.P., Pontikaki A., Velegrakis A., Papaioannou G.I., Koukoura O., Spandidos D.A., Papantoniou N. (2018)Fetal growth restriction (FGR) is a gynecological disorder of varying etiology. In the present study, an expression analysis of pregnancy-associated plasma protein A (PAPPA), pregnancy-associated plasma protein A2 (PAPPA2) ... -
Increased risk of non-alcoholic fatty liver disease in women with gestational diabetes mellitus: A population-based cohort study, systematic review and meta-analysis
Lavrentaki A., Thomas T., Subramanian A., Valsamakis G., Thomas N., Toulis K.A., Wang J., Daly B., Saravanan P., Sumilo D., Mastorakos G., Tahrani A.A., Nirantharakumar K. (2019)Aims: Non-Alcoholic Fatty Liver Disease (NAFLD) is one of the leading causes of liver transplantation in the West. This study seeks to examine whether women with gestational diabetes mellitus (GDM) are at increased risk ...