Seven months of aerobic intradialytic exercise training can prevent muscle loss in haemodialysis patients: an ultrasonography study
Ημερομηνία
2022Γλώσσα
en
Λέξη-κλειδί
Επιτομή
Purpose: This study aimed to evaluate the effects of 7-month intradialytic exercise training (IDE) on vastus lateralis (VL) muscle architecture, functional capacity and quality of life in stable haemodialysis (HD) patients. Methods: 44 HD patients were randomly assigned into an Exercise Group (EG = 21), which they received 7 months of IET, at 60% of pre-assessed maximum aerobic power, 3/week) or into a Control Group (CG = 23, no exercise). VL architecture was evaluated with ultrasonography, functional capacity was assessed using a series of functional tests (6 min walking test, 5 repetitions sit-to-stand, sit-to-stand 60 s, handgrip strength), and maximal aerobic power determined with a modified version of the Åstrand test. Quality of life and fatigue levels were evaluated using validated questionnaires. Results: VL fascicle angle and length did not change significantly in both groups (P > 0.05). Muscle thickness decreased in CG (P = 0.02) while it was fully preserved in the EG. Functional capacity increased only in the EG (6 min walking test 15.79 ± 12.35%, P < 0.001; max aerobic power 26.36 ± 1.24%, P < 0.001; STS-60rep: 10.23 ± 1.60%, P < 0.000; hand grip strength: 5.14 ± 28.30%, P < 0.02). Conclusion: Intradialytic aerobic exercise training, improves functional capacity and prevents thigh muscle mass loss in HD patients. It is evident that muscle ultrasonography could play a pivotal role in assessing muscle quality changes in haemodialysis patients. A higher level of training intensity or combination with resistance exercises may be required to further improve anabolism and influence muscle architecture in this patient population. Clinical Trial Registry number: NCT03905551. © 2021, The Author(s), under exclusive licence to Springer Nature B.V.
Collections
Related items
Showing items related by title, author, creator and subject.
-
The effects of training with high-speed interval running on muscle performance are modulated by slope
Theofilidis G., Bogdanis G.C., Stavropoulos-Kalinoglou A., Krase A.A., Tsatalas T., Shum G., Sakkas G.K., Koutedakis Y., Karatzaferi C. (2021)We examined changes in selected muscle performance parameters after 8 weeks of interval training using two opposite running inclinations. We hypothesized that the uphill training will affect endurance muscle performance ... -
The redox-dependent regulation of satellite cells following aseptic muscle trauma (SpEED): Study protocol for a randomized controlled trial
Papanikolaou K., Draganidis D., Chatzinikolaou A., Laschou V.C., Georgakouli K., Tsimeas P., Batrakoulis A., Deli C.K., Jamurtas A.Z., Fatouros I.G. (2019)Background: Muscle satellite cells (SCs) are crucial for muscle regeneration following muscle trauma. Acute skeletal muscle damage results in inflammation and the production of reactive oxygen species (ROS) which may be ... -
Iron Supplementation Effects on Redox Status following Aseptic Skeletal Muscle Trauma in Adults and Children
Deli C.K., Fatouros I.G., Paschalis V., Tsiokanos A., Georgakouli K., Zalavras A., Avloniti A., Koutedakis Y., Jamurtas A.Z. (2017)Exercise-induced skeletal muscle microtrauma is characterized by loss of muscle cell integrity, marked aseptic inflammatory response, and oxidative stress. We examined if iron supplementation would alter redox status after ...