Meta-analysis in Stata using gllamm
Abstract
There are several user-written programs for performing meta-analysis in Stata (Stata Statistical Software: College Station, TX: Stata Corp LP). These include metan, metareg, mvmeta, and glst. However, there are several cases for which these programs do not suffice. For instance, there is no software for performing univariate meta-analysis with correlated estimates, for multilevel or hierarchical meta-analysis, or for meta-analysis of longitudinal data. In this work, we show with practical applications that many disparate models, including but not limited to the ones mentioned earlier, can be fitted using gllamm. The software is very versatile and can handle a wide variety of models with applications in a wide range of disciplines. The method presented here takes advantage of these modeling capabilities and makes use of appropriate transformations, based on the Cholesky decomposition of the inverse of the covariance matrix, known as generalized least squares, in order to handle correlated data. The models described earlier can be thought of as special instances of a general linear mixed-model formulation, but to the author's knowledge, a general exposition in order to incorporate all the available models for meta-analysis as special cases and the instructions to fit them in Stata has not been presented so far. Source code is available at http:www.compgen.org/tools/gllamm. © 2015 John Wiley & Sons, Ltd.
Collections
Related items
Showing items related by title, author, creator and subject.
-
Demographic window to aging in the wild: Constructing life tables and estimating survival functions from marked individuals of unknown age
Müller, H. G.; Wang, J. L.; Carey, J. R.; Caswell-Chen, E. P.; Chen, C.; Papadopoulos, N.; Yao, F. (2004)We address the problem of establishing a survival schedule for wild populations. A demographic key identity is established, leading to a method whereby age-specific survival and mortality can be deduced from a marked cohort ... -
Assessment of natural and anthropogenic impacts in groundwater, utilizing multivariate statistical analysis and inverse distance weighted interpolation modeling: the case of a Scopia basin (Central Greece)
Charizopoulos N., Zagana E., Psilovikos A. (2018)In Scopia basin, central Greece, a hydrochemical investigation was completed. Groundwater samples from 41 sites were used to assess the natural and anthropogenic impacts in groundwater, utilizing the principal component ... -
Generalization of Youden index for multiple-class classification problems applied to the assessment of externally validated cognition in Parkinson disease screening
Nakas, C. T.; Dalrymple-Alford, J. C.; Anderson, T.; Alonzo, T. A. (2013)Routine cognitive screening in Parkinson disease (PD) has become essential for management, to track progression and to assess clinical status in therapeutic trials. Patients with mild cognitive impairment (PD-MCI) are more ...