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Transosseous application of low-intensity ultrasound at the tendon-bone interface affects the healing rate and up-regulates simultaneously the expression of collagen type i and tRNAGly

dc.creatorPapatheodorou, L. K.en
dc.creatorGrafanaki, K.en
dc.creatorGiannouli, S.en
dc.creatorFotiadis, D. I.en
dc.creatorStathopoulos, C.en
dc.creatorMalizos, K. N.en
dc.date.accessioned2015-11-23T10:44:30Z
dc.date.available2015-11-23T10:44:30Z
dc.date.issued2008
dc.identifier10.1109/BIBE.2008.4696755
dc.identifier.isbn9781424428458
dc.identifier.urihttp://hdl.handle.net/11615/31953
dc.description.abstractThe present study investigates the effect of transosseous low-intensity pulsed ultrasound (LiUS) during lingamentization process on the healing at tendon graft-bone interface in rabbits. Analysis of the RT-PCR products showed statistically significant up-regulation of genes encoding collagen type I and tRNAGly in the study group compared to the control group. Histological examination indicated a faster healing rate and a more efficient lingamentization process after ultrasound treatment. Our results suggest that transosseous application of LiUS enhances the healing rate of the tendon graft-bone interface, possibly by affecting the expression levels of significant genes.en
dc.source.urihttp://www.scopus.com/inward/record.url?eid=2-s2.0-67549086879&partnerID=40&md5=ac1e68ef701135f3f6ff2026ae927f23
dc.subjectCollagen type Ien
dc.subjectControl groupsen
dc.subjectExpression levelsen
dc.subjectGenes encodingen
dc.subjectHistological examinationen
dc.subjectLow intensity ultrasounden
dc.subjectLow-intensity pulsed ultrasounden
dc.subjectPCR productsen
dc.subjectStudy Groupsen
dc.subjectTendon graftsen
dc.subjectUltrasound treatmentsen
dc.subjectUp-regulationen
dc.subjectAcoustic wavesen
dc.subjectBioinformaticsen
dc.subjectBoneen
dc.subjectCollagenen
dc.subjectGenesen
dc.subjectGrafting (chemical)en
dc.subjectTendonsen
dc.subjectUltrasonicsen
dc.titleTransosseous application of low-intensity ultrasound at the tendon-bone interface affects the healing rate and up-regulates simultaneously the expression of collagen type i and tRNAGlyen
dc.typeconferenceItemen


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