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Blood reflects tissue oxidative stress: a systematic review

dc.creatorMargaritelis, N. V.en
dc.creatorVeskoukis, A. S.en
dc.creatorPaschalis, V.en
dc.creatorVrabas, I. S.en
dc.creatorDipla, K.en
dc.creatorZafeiridis, A.en
dc.creatorKyparos, A.en
dc.creatorNikolaidis, M. G.en
dc.date.accessioned2015-11-23T10:38:51Z
dc.date.available2015-11-23T10:38:51Z
dc.date.issued2015
dc.identifier10.3109/1354750x.2014.1002807
dc.identifier.issn1354-750X
dc.identifier.urihttp://hdl.handle.net/11615/30695
dc.description.abstractWe examined whether the levels of oxidative stress biomarkers measured in blood reflect the tissue redox status. Data from studies that measured redox biomarkers in blood, heart, liver, kidney and skeletal muscle were analyzed. In seven out of nine investigated redox biomarkers (malondialdehyde, reduced glutathione, superoxide dismutase, catalase, glutathione peroxidase, vitamin C and E) there was generally good qualitative and quantitative agreement between the blood and tissues. In contrast, oxidized glutathione and the reduced to oxidized glutathione ratio showed poor agreement between the blood and tissues. This study suggests that most redox biomarkers measured in blood adequately reflect tissue redox status.en
dc.source.uri<Go to ISI>://WOS:000358062100001
dc.subjectAntioxidanten
dc.subjectbiomarkersen
dc.subjectblooden
dc.subjectmuscleen
dc.subjectoxidative stressen
dc.subjecttissuesen
dc.subjectISCHEMIA-REPERFUSION INJURYen
dc.subjectISOPROTERENOL-INDUCED CARDIOTOXICITYen
dc.subjectPLASMA BIOCHEMICAL PARAMETERSen
dc.subjectINDUCED DIABETIC-RATSen
dc.subjectVITAMIN-Een
dc.subjectIN-VIVOen
dc.subjectWISTAR RATSen
dc.subjectMYOCARDIAL-INFARCTIONen
dc.subjectANTIOXIDATIVE DEFENSEen
dc.subjectLIPID-PEROXIDATIONen
dc.subjectBiotechnology & Applied Microbiologyen
dc.subjectToxicologyen
dc.titleBlood reflects tissue oxidative stress: a systematic reviewen
dc.typejournalArticleen


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