dc.creator | Fragkou, I. A. | en |
dc.creator | Skoufos, J. | en |
dc.creator | Cripps, P. J. | en |
dc.creator | Kyriazakis, I. | en |
dc.creator | Papaioannou, N. | en |
dc.creator | Boscos, C. M. | en |
dc.creator | Tzora, A. | en |
dc.creator | Fthenakis, G. C. | en |
dc.date.accessioned | 2015-11-23T10:26:46Z | |
dc.date.available | 2015-11-23T10:26:46Z | |
dc.date.issued | 2007 | |
dc.identifier | 10.1017/s0022029907002518 | |
dc.identifier.issn | 0022-0299 | |
dc.identifier.uri | http://hdl.handle.net/11615/27570 | |
dc.description.abstract | We used a Mannheimia haemolytica isolate to study differences in susceptibility to experimental mastitis between two breeds of dairy sheep. The isolate was deposited into the teat duct of Karagouniko (K, n=8) or Frisarta (F, n=8) ewes. The animals were monitored by means of clinical, bacteriological, cytological and pathological methods. K ewes did not develop any systemic or mammary clinical signs, whilst F ewes became ill and developed acute clinical mastitis 12 h later (P < 0.001). Bacteria were isolated from 34/48 samples from K ewes and from 46/46 samples from F ewes. Positive California mastitis test (CMT) results were 17/24 samples from K ewes and 23/23 samples from F ewes; leucocytes were seen in Giemsa-stained films. Total pathology score summed over all group K ewes was 41 (maximum possible: 128); Man. haemolytica was isolated from 12/24 tissue samples. Total pathology score summed over all group F ewes was 93; Man. haemolytica was isolated from 24/24 tissue samples. Hyperplastic lymphoid nodules consisting of lymphocytes and plasma cells with germinal activity were characteristically present at the border between teat duct-teat cistern of group K ewes; no such structures were observed in teats of group F ewes. The results identified differences in susceptibility/resistance to a mastitis pathogen among animals of the two breeds. Defence mechanisms of the teat appeared to be inadequate against the invading organisms; as lymphoid nodules have been considered important defensive mechanisms of the ovine teat, their observed lack in Frisarta ewes might have predisposed them to development of mastitis. | en |
dc.source | Journal of Dairy Research | en |
dc.source.uri | <Go to ISI>://WOS:000249507200015 | |
dc.subject | sheep | en |
dc.subject | mastitis | en |
dc.subject | Mannheimia haemolytica | en |
dc.subject | breed susceptibility | en |
dc.subject | SOMATIC-CELL COUNT | en |
dc.subject | MAJOR HISTOCOMPATIBILITY COMPLEX | en |
dc.subject | PERIPARTURIENT | en |
dc.subject | HOLSTEIN CATTLE | en |
dc.subject | INDUCED SUBCLINICAL MASTITIS | en |
dc.subject | INTRAMAMMARY INFECTION | en |
dc.subject | MILK-YIELD | en |
dc.subject | EWES | en |
dc.subject | INOCULATION | en |
dc.subject | PARAMETERS | en |
dc.subject | TEAT | en |
dc.subject | Agriculture, Dairy & Animal Science | en |
dc.subject | Food Science & Technology | en |
dc.title | Differences in susceptibility to Mannheimia haemolytica-associated mastitis between two breeds of dairy sheep | en |
dc.type | journalArticle | en |