• Epigenetic regulation of hTERT promoter in hepatocellular carcinomas 

      Iliopoulos, D.; Satra, M.; Drakaki, A.; Poultsides, G. A.; Tsezou, A. (2009)
      Although hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide, the molecular pathogenesis of the disease has not been elucidated. Several studies have shown that telomerase activity and hTERT expression ...
    • hTERT regulation by NF-kappa B and c-myc in irradiated HER2-positive breast cancer cells 

      Papanikolaou, V.; Athanassiou, E.; Dubos, S.; Dimou, I.; Papathanasiou, I.; Kitsiou-Tzeli, S.; Kappas, C.; Tsezou, A. (2011)
      Purpose: Telomerase activity (TA), frequently observed in cancer, compensates for telomere shortening thus preventing cell senescence and conferring resistance to therapy. In the present study, we investigated the expression ...
    • Survivin regulation by HER2 through NF-kappa B and c-myc in irradiated breast cancer cells 

      Papanikolaou, V.; Iliopoulos, D.; Dimou, I.; Dubos, S.; Kappas, C.; Kitsiou-Tzeli, S.; Tsezou, A. (2011)
      Radiotherapy is an important treatment modality against cancer resulting in apoptosis and inhibition of cell growth. Survivin is an important cancer biomarker conferring to tumour cells increased survival potential by ...