Πλοήγηση ανά Θέμα "UP-REGULATION"
Αποτελέσματα 1-7 από 7
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ANTIANGIOGENIC POTENTIAL OF GRAPE STEM EXTRACT THROUGH INHIBITION OF VASCULAR ENDOTHELIAL GROWTH FACTOR EXPRESSION
(2014)The aim of the present study was to investigate the antiangiogenic potential of a grape stem extract against tube formation by human endothelial cells (EA.hy926). The results showed that at low and non-cytotoxic concentrations ... -
The existence of two types of proteasome, the constitutive proteasome and the immunoproteasome, may serve as another layer of protection against autoimmunity
(2012)Negative selection of CD8 single positive thymocytes is based on the presentation through the major histocompatibility complex (MHC) class I pathway of peptides derived from degradation of self-proteins by the constitutive ... -
Implications of pleiotrophin in human PC3 prostate cancer cell growth in vivo
(2012)Pleiotrophin (PTN) is a heparin-binding growth factor with diverse functions related to tumor growth, angiogenesis, and metastasis. Pleiotrophin seems to have a significant role in prostate cancer cell growth and to mediate ... -
MgcRacGAP interacts with HIF-1 alpha and regulates its transcriptional activity
(2007)HIF-1 alpha is the inducible subunit of the dimeric transcription factor HIF-1 (Hypoxia Inducible Factor 1). It is induced by hypoxia and hypoxia-mimetics in most cell types, as well as non-hypoxic signals such as growth ... -
Oral squamous cell cancer: early detection and the role of alcohol and smoking
(2011)Objective: Oral squamous cell carcinoma has a remarkable incidence worldwide and a fairly onerous prognosis, encouraging further research on factors that might modify disease outcome. Data sources: A web-based search for ... -
PKC-epsilon activation is required for recognition memory in the rat
(2013)Activation of PKC epsilon, an abundant and developmentally regulated PKC isoform in the brain, has been implicated in memory throughout life and across species. Yet, direct evidence for a mechanistic role for PKC epsilon ... -
Telomerase reverse transcriptase mRNA expression in peripheral lymphocytes of patients with chronic HBV and HCV infections
(2005)Telomerase activity is present at low levels in peripheral lymphocytes (PL) and is upregulated upon activation, possibly protecting PL from telomere shortening. As decreased telomere length is considered a sign of cellular ...