• Absence of linkage to chromosomes 6q and 16p in a Greek population with knee osteoarthritis 

      Tsezou, A.; Karachalios, T.; Fytili, P.; Giannatou, E.; Christodoulou, K.; Hadjigeorgiou, G. M.; Malizos, K. N. (2006)
      Osteoarthritis (OA) is a common age-related debilitating disease of the joints characterized by degeneration of the articular cartilage which leads to joint pain, discomfort, and immobility. Several risk factors have been ...
    • Assessment of Osteoarthritis Candidate Genes in a Meta-Analysis of Nine Genome-Wide Association Studies 

      Rodriguez-Fontenla, C.; Calaza, M.; Evangelou, E.; Valdes, A. M.; Arden, N.; Blanco, F. J.; Carr, A.; Chapman, K.; Deloukas, P.; Doherty, M.; Esko, T.; Aleta, C. M. G.; Carnota, Jjgr; Helgadottir, H.; Hofman, A.; Jonsdottir, I.; Kerkhof, H. J. M.; Kloppenburg, M.; McCaskie, A.; Ntzani, E. E.; Ollier, W. E. R.; Oreiro, N.; Panoutsopoulou, K.; Ralston, S. H.; Ramos, Y. F.; Riancho, J. A.; Rivadeneira, F.; Slagboom, P. E.; Styrkarsdottir, U.; Thorsteinsdottir, U.; Thorleifsson, G.; Tsezou, A.; Uitterlinden, A. G.; Wallis, G. A.; Wilkinson, J. M.; Zhai, G. J.; Zhu, Y. Y.; Felson, D. T.; Ioannidis, J. P. A.; Loughlin, J.; Metspalu, A.; Meulenbelt, I.; Stefansson, K.; van Meurs, J. B.; Zeggini, E.; Spector, T. D.; Gonzalez, A.; arc, Ogen Consortium (2014)
      Objective. To assess candidate genes for association with osteoarthritis (OA) and identify promising genetic factors and, secondarily, to assess the candidate gene approach in OA. Methods. A total of 199 candidate genes ...
    • Clinical applications of intracranial pressure monitoring in traumatic brain injury 

      Stocchetti, N.; Picetti, E.; Berardino, M.; Buki, A.; Chesnut, R. M.; Fountas, K. N.; Horn, P.; Hutchinson, P. J.; Iaccarino, C.; Kolias, A. G.; Koskinen, L. O.; Latronico, N.; Maas, A. I. R.; Payen, J. F.; Rosenthal, G.; Sahuquillo, J.; Signoretti, S.; Soustiel, J. F.; Servadei, F. (2014)
      Intracranial pressure (ICP) monitoring has been for decades a cornerstone of traumatic brain injury (TBI) management. Nevertheless, in recent years, its usefulness has been questioned in several reports. A group of ...
    • Field Synopsis and Synthesis of Genetic Association Studies in Osteoarthritis: The CUMAGAS-OSTEO Information System 

      Zintzaras, E.; Kitsios, G. D.; Ziogas, D. C.; Rodopoulou, P.; Karachalios, T. (2010)
      A comprehensive and systematic assessment of the current status of genetic association studies (GAS) for osteoarthntis was conducted. Data from 327 GAS involving 187 distinct genetic variants were analyzed and cataloged ...
    • Heterogeneity testing in meta-analysis of genome searches 

      Zintzaras, E.; Ioannidis, J. P. A. (2005)
      Genome searches for identifying susceptibility loci for the same complex disease often give inconclusive or inconsistent results. Genome Search Meta-analysis (GSMA) is an established non-parametric method to identify genetic ...
    • A heterogeneity-based genome search meta-analysis for autism-spectrum disorders 

      Trikalinos, T. A.; Karvouni, A.; Zintzaras, E.; Ylisaukko-oja, T.; Peltonen, L.; Jarvela, I.; Ioannidis, J. P. A. (2006)
      Autism and autism-spectrum disorders exhibit high heritability, although specific susceptibility genes still remain largely elusive. We performed a heterogeneity-based genome search meta-analysis (HEGESMA) of nine genome ...
    • Heterogeneity-based genome search meta-analysis for preeclampsia 

      Zintzaras, E.; Kitsios, G.; Harrison, G. A.; Laivuori, H.; Kivinen, K.; Kere, J.; Messinis, I.; Stefanidis, I.; Ioannidis, J. P. A. (2006)
      Preeclampsia is a pregnancy-related disorder that causes maternal and fetal morbidity and mortality. Its exact inheritance pattern is still unknown, and genome searches for identifying susceptibility loci for preeclampsia ...