• Apremilast increases IL-10-producing regulatory B cells and decreases proinflammatory T cells and innate cells in psoriatic arthritis and psoriasis 

      Mavropoulos A., Zafiriou E., Simopoulou T., Brotis A.G., Liaskos C., Roussaki-Schulze A., Katsiari C.G., Bogdanos D.P., Sakkas L.I. (2019)
      Objectives: Psoriatic arthritis (PsA) and psoriasis are immune-mediated inflammatory diseases sharing common immunological mechanisms. Regulatory B cells (Breg cells) producing IL-10 (B10 cells), a critical anti-inflammatory ...
    • Biologics in SAPHO syndrome: A systematic review 

      Daoussis D., Konstantopoulou G., Kraniotis P., Sakkas L., Liossis S.-N. (2019)
      Background: The SAPHO syndrome is a relatively rare clinical entity characterized by a wide range of dermatological and musculoskeletal manifestations. Biologics have been used in cases refractory to conventional treatment. ...
    • Children with psoriasis and COVID-19: factors associated with an unfavourable COVID-19 course, and the impact of infection on disease progression (Chi-PsoCov registry) 

      Zitouni J., Bursztejn A.-C., Belloni Fortina A., Beauchet A., Di Lernia V., Lesiak A., Thomas J., Topkarci Z., Murashkin N., Brzezinski P., Torres T., Chiriac A., Luca C., McPherson T., Akinde M., Maruani A., Epishev R., Vidaurri de la Cruz H., Luna P.C., Amy de la Bretêque M., Lasek A., Bourrat E., Bachelerie M., Mallet S., Steff M., Bellissen A., Neri I., Zafiriou E., van den Reek J.M.P.A., Sonkoly E., Mahil S.K., Smith C.H., Flohr C., Bachelez H., Mahé E., the Groupe de Recherche sur le Psoriasis (GrPso) of the Societe Francaise de Dermatologie, the Groupe de recherche de la Societe Francaise de Dermatologie Pediatrique (GR SFDP), the PsoProtect study group, the British Society of Paediatric Dermatology (BPSD), and the Societa Italiana di Dermatologia Pediatrica (S.I.Der.P.) (2022)
      Background: The COVID-19 pandemic has raised questions regarding the management of chronic skin diseases, especially in patients on systemic treatments. Data concerning the use of biologics in adults with psoriasis are ...
    • Mini review: New treatments in psoriatic arthritis. Focus on the IL-23/17 Axis 

      Sakkas L.I., Zafiriou E., Bogdanos D.P. (2019)
      Psoriasis, an inflammatory skin disease, and psoriatic arthritis (PsA), an inflammatory arthritis, share clinical, genetic, and pathogenic factors and may be summed as one disease, the psoriatic disease. Interleukin (IL)-17 ...
    • Real world experience of brodalumab treatment in patients with moderate-to-severe plaque psoriasis in the Greek population: Results from an interim analysis of the BrIDGE study 

      Rigopoulos D., Angelakopoulos C., Apalla Z., Georgiou S., Delli F., Drosos A., Zafiriou E., Katsantonis J., Lazaridou E., Panagakis P., Papadavid E., Papakonstantis M., Roussaki-Schulze A.-V., Sotiriou E., Anastasiadis G., Tampouratzi E., Chasapi V., Sfaelos K., Ioannides D., The BrIDGE Study Group (2022)
      Brodalumab's clinical efficacy and favorable safety profile have been demonstrated during controlled clinical trials, but real-world data remain scarce. BrIDGE, an ongoing 104 week, observational, prospective, multicenter ...
    • Real-world safety and efficacy data of immunotherapy in patients with cancer and autoimmune disease: the experience of the Hellenic Cooperative Oncology Group 

      Fountzilas E., Lampaki S., Koliou G.-A., Koumarianou A., Levva S., Vagionas A., Christopoulou A., Laloysis A., Psyrri A., Binas I., Mountzios G., Kentepozidis N., Kotsakis A., Saloustros E., Boutis A., Nikolaidi A., Fountzilas G., Georgoulias V., Chrysanthidis M., Kotteas E., Vo H., Tsiatas M., Res E., Linardou H., Daoussis D., Bompolaki I., Andreadou A., Papaxoinis G., Spyratos D., Gogas H., Syrigos K.N., Bafaloukos D. (2022)
      Background: Data on the safety and efficacy of immune checkpoint inhibitors (ICI) in patients with concurrent autoimmune diseases (AID) are limited. Methods: We performed a retrospective multicenter review of medical records ...
    • Smoke and autoimmunity: The fire behind the disease 

      Perricone C., Versini M., Ben-Ami D., Gertel S., Watad A., Segel M.J., Ceccarelli F., Conti F., Cantarini L., Bogdanos D.P., Antonelli A., Amital H., Valesini G., Shoenfeld Y. (2016)
      The association between smoke habit and autoimmunity has been hypothesized a long time ago. Smoke has been found to play a pathogenic role in certain autoimmune disease as it may trigger the development of autoantibodies ...