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Πλοήγηση ανά Θέμα "untranslated RNA"

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    • Characterizing miRNA–lncRNA Interplay 

      Karagkouni D., Karavangeli A., Paraskevopoulou M.D., Hatzigeorgiou A.G. (2021)
      Long noncoding RNAs (lncRNAs) are noncoding transcripts, usually longer than 200 nt, that constitute one of the largest and significantly heterogeneous RNA families. The annotation of lncRNAs and the characterization of ...

    • Circulating biomarkers for cardiovascular diseases: The beats never stop editorial 

      Xi L., Kouvelos G., Paolocci N. (2018)
      [No abstract available]

    • DIANA-LncBase v2: Indexing microRNA targets on non-coding transcripts 

      Paraskevopoulou M.D., Vlachos I.S., Karagkouni D., Georgakilas G., Kanellos I., Vergoulis T., Zagganas K., Tsanakas P., Floros E., Dalamagas T., Hatzigeorgiou A.G. (2016)
      MicroRNAs (miRNAs) are short non-coding RNAs (ncRNAs) that act as post-transcriptional regulators of coding gene expression. Long non-coding RNAs (lncRNAs) have been recently reported to interact with miRNAs. The sponge-like ...

    • DIANA-LncBase v3: Indexing experimentally supported miRNA targets on non-coding transcripts 

      Karagkouni D., Paraskevopoulou M.D., Tastsoglou S., Skoufos G., Karavangeli A., Pierros V., Zacharopoulou E., Hatzigeorgiou A.G. (2020)
      DIANA-LncBase v3.0 (www.microrna.gr/LncBase) is a reference repository with experimentally supported miRNA targets on non-coding transcripts. Its third version provides approximately half a million entries, corresponding ...

    • DIANA-TarBase v8: A decade-long collection of experimentally supported miRNA-gene interactions 

      Karagkouni D., Paraskevopoulou M.D., Chatzopoulos S., Vlachos I.S., Tastsoglou S., Kanellos I., Papadimitriou D., Kavakiotis I., Maniou S., Skoufos G., Vergoulis T., Dalamagas T., Hatzigeorgiou A.G. (2018)
      DIANA-TarBase v8 (http://www.microrna.gr/tarbase) is a reference database devoted to the indexing of experimentally supported microRNA (miRNA) targets. Its eighth version is the first database indexing >1 million entries, ...

    • Endocrine resistance and epigenetic reprogramming in estrogen receptor positive breast cancer 

      Dimitrakopoulos F.-I., Kottorou A., Tzezou A. (2021)
      Despite the enormous advances during the last three decades, breast cancer continues to be the most frequent type of cancer as well as one of the most frequent cancer-related causes of death in women. Therapeutic management ...

    • MicroRNAs and the Diagnosis of Childhood Acute Lymphoblastic Leukemia: Systematic Review, Meta-Analysis and Re-Analysis with Novel Small RNA-Seq Tools 

      Kyriakidis I., Kyriakidis K., Tsezou A. (2022)
      MicroRNAs (miRNAs) have been implicated in childhood acute lymphoblastic leukemia (ALL) pathogenesis. We performed a systematic review and meta-analysis of miRNA single-nucleotide polymorphisms (SNPs) in childhood ALL ...

    • microTSS: Accurate microRNA transcription start site identification reveals a significant number of divergent pri-miRNAs 

      Georgakilas, G.; Vlachos, I. S.; Paraskevopoulou, M. D.; Yang, P.; Zhang, Y.; Economides, A. N.; Hatzigeorgiou, A. G. (2014)
      A large fraction of microRNAs (miRNAs) are derived from intergenic non-coding loci and the identification of their promoters remains 'elusive'. Here, we present microTSS, a machine-learning algorithm that provides highly ...

    • Multi-branch Convolutional Neural Network for Identification of Small Non-coding RNA genomic loci 

      Georgakilas G.K., Grioni A., Liakos K.G., Chalupova E., Plessas F.C., Alexiou P. (2020)
      Genomic regions that encode small RNA genes exhibit characteristic patterns in their sequence, secondary structure, and evolutionary conservation. Convolutional Neural Networks are a family of algorithms that can classify ...

    • Non-coding RNAs in cancer-associated cachexia: clinical implications and future perspectives 

      Kottorou A., Dimitrakopoulos F.-I., Tsezou A. (2021)
      Cachexia is a multifactorial syndrome characterized by skeletal muscle loss, with or without adipose atrophy, irreversible through nutritional support, in the context of systemic inflammation and metabolic disorders. It ...

    • RNAcentral: A comprehensive database of non-coding RNA sequences 

      Petrov A.I., Kay S.J.E., Kalvari I., Howe K.L., Gray K.A., Bruford E.A., Kersey P.J., Cochrane G., Finn R.D., Bateman A., Kozomara A., Griffiths-Jones S., Frankish A., Zwieb C.W., Lau B.Y., Williams K.P., Chan P.P., Lowe T.M., Cannone J.J., Gutell R.R., Machnicka M.A., Bujnicki J.M., Yoshihama M., Kenmochi N., Chai B., Cole J.R., Szymanski M., Karlowski W.M., Wood V., Huala E., Berardini T.Z., Zhao Y., Chen R., Zhu W., Paraskevopoulou M.D., Vlachos I.S., Hatzigeorgiou A.G., Ma L., Zhang Z., Puetz J., Stadler P.F., McDonald D., Basu S., Fey P., Engel S.R., Cherry J.M., Volders P.-J., Mestdagh P., Wower J., Clark M., Quek X.C., Dinger M.E., The RNAcentral Consortium (2017)
      RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for accessing ncRNA sequences of all ncRNA types from all organisms. Since ...

    • RNAcentral: A hub of information for non-coding RNA sequences 

      Sweeney B.A., Petrov A.I., Burkov B., Finn R.D., Bateman A., Szymanski M., Karlowski W.M., Gorodkin J., Seemann S.E., Cannone J.J., Gutell R.R., Fey P., Basu S., Kay S., Cochrane G., Billis K., Emmert D., Marygold S.J., Huntley R.P., Lovering R.C., Frankish A., Chan P.P., Lowe T.M., Bruford E., Seal R., Vandesompele J., Volders P.-J., Paraskevopoulou M., Ma L., Zhang Z., Griffiths-Jones S., Bujnicki J.M., Boccaletto P., Blake J.A., Bult C.J., Chen R., Zhao Y., Wood V., Rutherford K., Rivas E., Cole J., Laulederkind S.J.F., Shimoyama M., Gillespie M.E., Orlic-Milacic M., Kalvari I., Nawrocki E., Engel S.R., Cherry J.M., Team S., Berardini T.Z., Hatzigeorgiou A., Karagkouni D., Howe K., Davis P., Dinger M., He S., Yoshihama M., Kenmochi N., Stadler P.F., Williams K.P. (2019)
      RNAcentral is a comprehensive database of non-coding RNA (ncRNA) sequences, collating information on ncRNA sequences of all types from a broad range of organisms. We have recently added a new genome mapping pipeline that ...