Gesamter Bestand

Auflistung Nach Schlagwort "monogenic disorder"

Anzeige der Dokumente 1-3 von 3

    • FV vectors as alternative gene vehicles for gene transfer in HSCs 

      Simantirakis E., Tsironis I., Vassilopoulos G. (2020)
      Hematopoietic Stem Cells (HSCs) are a unique population of cells, capable of reconstituting the blood system of an organism through orchestrated self-renewal and differentiation. They play a pivotal role in stem cell ...

    • Network analysis of genes and their association with diseases 

      Kontou P.I., Pavlopoulou A., Dimou N.L., Pavlopoulos G.A., Bagos P.G. (2016)
      A plethora of network-based approaches within the Systems Biology universe have been applied, to date, to investigate the underlying molecular mechanisms of various human diseases. In the present study, we perform a ...

    • Success Stories and Challenges Ahead in Hematopoietic Stem Cell Gene Therapy: Hemoglobinopathies as Disease Models 

      Yannaki E., Psatha N., Papadopoulou A., Athanasopoulos T., Gravanis A., Roubelakis M.G., Tsirigotis P., Anagnostopoulos A., Anagnou N.P., Vassilopoulos G. (2021)
      Gene therapy is a relatively novel field that amounts to around four decades of continuous growth with its good and bad moments. Currently, the field has entered the clinical arena with the ambition to fulfil its promises ...