Πλοήγηση ανά Θέμα "metastasis"

Acute myocardial infarction not attributed to coronary artery disease: A seldom initial presentation of a left ventricular myxoma

Spiliopoulos K., Anyfantakis Z.A., Diminikos I., Xanthopoulos A., Magouliotis D.E., Skoularigis J., Triposkiadis F. (2021)

Although myxoma represents the most frequent non-malignant cardiac primary tumor; it is extremely rare met in the left ventricle. Clinical features of the neoplasm extend from symptomless to critical signs of either ischemia ...

Alpha-actinin: A multidisciplinary protein with important role in B-cell driven autoimmunity

Kikonomou, K. G.; Zachou, K.; Dalekos, G. N. (2011)

Alpha-actinin (α-actinin) is a ubiquitous cytoskeletal protein, which belongs to the superfamily of filamentous actin (F-actin) crosslinking proteins. It is present in multiple subcellular regions of both muscle and ...

Application of efficient nanoparticles for early diagnosis and treatment of cancer

Alexiou A., Vairaktarakis C., Tsiamis V., Ashraf G.M. (2015)

Cancer is considered as a prevalent cause of human deaths and undoubtedly, is the most complex disease with multiple cellular physiological systems involved. During the last decade, the application of nanotechnological ...

Assessment of the efficacy and clinical utility of different circulating tumor cell (CTC) detection assays in patients with chemotherapy-naïve advanced or metastatic non-small cell lung cancer (NSCLC)

Papadaki M.A., Messaritakis I., Fiste O., Souglakos J., Politaki E., Kotsakis A., Georgoulias V., Mavroudis D., Agelaki S. (2021)

We herein investigated the detection frequency and clinical relevance of circulating tumor cells (CTCs) in chemotherapy-naïve stage IIIB/IV non-small cell lung cancer (NSCLC), by using the CellSearch and real-time CEACAM5mRNA ...

Biomarkers in prostate-specific membrane antigen theranostics

Vlachostergios P.J., Zachos I., Tzortzis V. (2021)

Theranostics of prostate cancer (PC) represents a growing area of development of imaging agents and targeted radionuclide therapeutics against a major target, prostate specific membrane antigen (PSMA). In view of the ...

A Case of Cervical Carcinoid and Review of the Literature

Papatsimpas G., Samaras I., Theodosiou P., Papacharalampous K., Maragkouli E., Papadopoulos N.V., Tsapakidis K., Litos I., Sogka E., Kostopoulou E., Koukoulis G.K. (2017)

Uterine cervix carcinoids are distinct neuroendocrine cervical tumors, representing a comparatively small percentage of them. These well-differentiated neoplasms are far less prevalent than small-and large-cell carcinomas, ...

CD90/Thy-1, a cancer-associated cell surface signaling molecule

Sauzay C., Voutetakis K., Chatziioannou A.A., Chevet E., Avril T. (2019)

CD90 is a membrane GPI-anchored protein with one Ig V-type superfamily domain that was initially described in mouse T cells. Besides the specific expression pattern and functions of CD90 that were described in normal tissues ...

Circulating tumor cells as prognostic biomarkers in breast cancer: current status and future prospects

Chantzara E., Xenidis N., Kallergi G., Georgoulias V., Kotsakis A. (2021)

Introduction : Despite advances in diagnostic and therapeutic techniques breast cancer is still associated with significant morbidity and mortality. CTCs play a crucial role in the metastatic process, which is the main ...

Depletion of Ras Suppressor-1 (RSU-1) promotes cell invasion of breast cancer cells through a compensatory upregulation of a truncated isoform

Gkretsi V., Kalli M., Efstathiades C., Papageorgis P., Papanikolaou V., Zacharia L.C., Tsezou A., Athanassiou E., Stylianopoulos T. (2019)

Extracellular matrix (ECM)-adhesion proteins and actin cytoskeleton are pivotal in cancer cell invasion. Ras Suppressor-1 (RSU-1), a cell-ECM adhesion protein that interacts with PINCH-1, thus being connected to Integrin ...

Differentiation of glioblastoma multiforme from metastatic brain tumor using proton magnetic resonance spectroscopy, diffusion and perfusion metrics at 3 T

Tsougos, I.; Svolos, P.; Kousi, E.; Fountas, K.; Theodorou, K.; Fezoulidis, I.; Kapsalaki, E. (2012)

Purpose: To assess the contribution of H-1-magnetic resonance spectroscopy (H-1-MRS), diffusion-weighted imaging (DWI), diffusion tensor imaging (DTI) and dynamic susceptibility contrast-enhanced (DSCE) imaging metrics in ...

Dynamic changes of CTCs in patients with metastatic HR(+)/HER2(−) breast cancer receiving salvage treatment with everolimus/exemestane

Spiliotaki M., Kallergi G., Nikolaou C., Xenidis N., Politaki E., Apostolaki S., Georgoulia N., Koinis F., Tsoukalas N., Hatzidaki D., Kotsakis A., Georgoulias V. (2021)

Purpose: Detection of CTCs represents a poor prognostic factor in patients with early and metastatic breast cancer (mBC) and treatment with everolimus–exemestane (E/E) is an established effective treatment in hormone ...

FDG-PET for detecting local tumor recurrence of ablated liver metastases: a diagnostic meta-analysis

Poulou, L. S.; Ziakas, P. D.; Ziogas, D. C.; Doxani, C.; Xyla, V.; Vakrinos, G.; Voulgarelis, M.; Thanos, L. (2012)

Context: Scanty reports have focused on FDG-PET after radiofrequency ablation (RFA), for recurrence of hepatic metastases. Objective: To assess FDG-PET diagnostic accuracy on detection of recurrent hepatic lesions. Methods: ...

High-risk pituitary adenomas and strategies for predicting response to treatment

Kontogeorgos G., Thodou E., Osamura R.Y., Lloyd R.V. (2022)

High-risk pituitary adenomas are aggressive. They show clinical and imaging features similar to those of carcinomas, including infiltration of the surrounding brain structures, but lack cerebrospinal or systemic metastases. ...

Identification of human papillomavirus DNA in melanoma biopsy specimens of Greek population

Roussaki-Schulze, A. V.; Kouskoukis, C.; Rammos, C.; Rallis, E.; Kontos, F.; Zafiriou, E.; Gross, G. (2005)

The aim of this retrospective study was to evaluate melanoma biopsy specimens from the Greek population living in the prefecture of Larissa for the presence of human papillomavirus (HPV) DNA and to determine the possible ...

Increasing incidence of melanoma in central Greece: A retrospective epidemiology study

Roussaki-Schulze, A. V.; Rammos, C.; Rallis, E.; Terzis, A.; Archontonis, N.; Sarmanta, A.; Klimi, E.; Zafiriou, E. (2005)

The increasing incidence of melanoma in the general population during the last few decades has provoked a great deal of research, aiming to identify the possible relationship between old and new etiological factors involved ...

Investigating Molecular Determinants of Cancer Cell Resistance to Ionizing Radiation Through an Integrative Bioinformatics Approach

Toy H.I., Karakülah G., Kontou P.I., Alotaibi H., Georgakilas A.G., Pavlopoulou A. (2021)

Eradication of cancer cells through exposure to high doses of ionizing radiation (IR) is a widely used therapeutic strategy in the clinical setting. However, in many cases, cancer cells can develop remarkable resistance ...