Πλοήγηση ανά Θέμα "immune deficiency"

Chloramphenicol derivatives as antibacterial and anticancer agents: Historic problems and current solutions

Dinos G.P., Athanassopoulos C.M., Missiri D.A., Giannopoulou P.C., Vlachogiannis I.A., Papadopoulos G.E., Papaioannou D., Kalpaxis D.L. (2016)

Chloramphenicol (CAM) is the D-threo isomer of a small molecule, consisting of a p-nitrobenzene ring connected to a dichloroacetyl tail through a 2-amino-1,3-propanediol moiety. CAM displays a broad-spectrum bacteriostatic ...

Enigma variations: The multi-faceted problems of pre-school wheeze

Chatziparasidis G., Bush A. (2022)

Numerous publications on wheezing disorders in children younger than 6 years have appeared in the medical literature over the last decades with the aim of shedding light on the mechanistic pathways (endotypes) and treatment. ...

Index of suspicion

Kaditis, A. G.; Gourgoulianis, K.; Jain, S. K. (2001)

Myeloid-derived suppressor cells: Major figures that shape the immunosuppressive and angiogenic network in cancer

Vetsika E.-K., Koukos A., Kotsakis A. (2019)

Myeloid-derived suppressor cells (MDSCs) constitute a vast population of immature myeloid cells implicated in various conditions. Most notably, their role in cancer is of great complexity. They exert immunosuppressive ...

Prehospital NSAIDs use prolong hospitalization in patients with pleuro-pulmonary infection

Kotsiou O.S., Zarogiannis S.G., Gourgoulianis K.I. (2017)

Objective Nonsteroidal anti-inflammatory drug (NSAID) pre-hospitalization consumption might affect the course of pneumonia. We opted to assess the potential effects of pre-hospitalization use of NSAIDs in patients with ...

Recent Advances in Aggressive Large B-cell Lymphomas: A Comprehensive Review

Korkolopoulou P., Vassilakopoulos T., Milionis V., Ioannou M. (2016)

Diffuse large B-cell lymphoma (DLBCL) is an aggressive disease with considerable heterogeneity reflected in the 2008 World Health Organization classification. In recent years, genome-wide assessment of genetic and epigenetic ...

SIAE Rare Variants in Juvenile Idiopathic Arthritis and Primary Antibody Deficiencies

Sevdali E., Tsitsami E., Tsinti M., Farmaki E., Papadopoulou-Alataki E., Germenis A.E., Speletas M. (2017)

Sialic acid acetylesterase (SIAE) deficiency was suggested to lower the levels of ligands for sialic acid-binding immunoglobulin-like receptors, decreasing the threshold for B-cell activation. In humans, studies of rare ...

Targeted and global pharmacometabolomics in everolimus-based immunosuppression: association of co-medication and lysophosphatidylcholines with dose requirement

Lesche D., Sigurdardottir V., Leichtle A.B., Nakas C.T., Christians U., Englberger L., Fiedler M., Largiadèr C.R., Mohacsi P., Sistonen J. (2018)

Introduction: The immunosuppressive therapy with everolimus (ERL) after heart transplantation is characterized by a narrow therapeutic window and a substantial variability in dose requirement. Factors explaining this ...

Vaccination Coverage of the Elderly in Greece: A Cross-Sectional Nationwide Study

Papagiannis D., Rachiotis G., Mariolis A., Zafiriou E., Gourgoulianis K.I. (2020)

Vaccines are important for older adults, and the morbidity and mortality of vaccine-preventable diseases among older adults are high. There are limited data on vaccination coverage among elderly people in Greece. The aim ...