• Anaesthetic and genotoxic effect of medicinal plant extracts in gilthead seabream (Sparus aurata L.) 

      Golomazou E., Malandrakis E.E., Kavouras M., Karatzinos T., Miliou H., Exadactylos A., Panagiotaki P. (2016)
      Anaesthetic properties and potential genotoxicity of six essential oils extracted from the medicinal plants Origanum vulgare, Eugenia aromatica, Aloysia triphylla, Melaleuca alternifolia, Juniperus communis, Cinnamomum ...
    • Assessment of antioxidant and antimutagenic properties of red and white wine extracts in vitro 

      Tekos F., Makri S., Skaperda Z.-V., Patouna A., Terizi K., Kyriazis I.D., Kotseridis Y., Mikropoulou E.V., Papaefstathiou G., Halabalaki M., Demetrios K. (2021)
      Wine is an alcoholic beverage of complex composition obtained through the fermentation of grape must. The consumption of wine has already been associated with a multitude of beneficial effects due to its high polyphenolic ...
    • Carbon nanotubes and other engineered nanoparticles induced pathophysiology on mesothelial cells and mesothelial membranes 

      Sinis S.I., Hatzoglou C., Gourgoulianis K.I., Zarogiannis S.G. (2018)
      Nanoparticles have great potential for numerous applications due to their unique physicochemical properties. However, concerns have been raised that they may induce deleterious effects on biological systems. There is ...
    • Chimeric stimuli-responsive liposomes as nanocarriers for the delivery of the anti-glioma agent TRAM-34 

      Naziris N., Pippa N., Sereti E., Chrysostomou V., Kędzierska M., Kajdanek J., Ionov M., Miłowska K., Balcerzak Ł., Garofalo S., Limatola C., Pispas S., Dimas K., Bryszewska M., Demetzos C. (2021)
      Nanocarriers are delivery platforms of drugs, peptides, nucleic acids and other therapeutic molecules that are indicated for severe human diseases. Gliomas are the most frequent type of brain tumor, with glioblastoma being ...
    • Contrast-induced nephropathy in an animal model: Evaluation of novel biomarkers in blood and tissue samples 

      Mamoulakis C., Fragkiadoulaki I., Karkala P., Georgiadis G., Zisis I.-E., Stivaktakis P., Kalogeraki A., Tsiaoussis I., Burykina T., Lazopoulos G., Tsarouhas K., Kouretas D., Tsatsakis A. (2019)
      Identification of novel biomarkers of contrast-induced nephropathy (CIN)that may more accurately detect renal function changes; reflect kidney damage; assist monitoring; and elucidate pathophysiology attract considerable ...
    • Effects of pesticides on exposed populations from four European countries 

      Piperakis, S. M.; Kontogianni, K.; Karanastasi, G.; Siffel, C.; Cebulska-Wasilewska, A.; Markos, R.; Iakovidou-Kritsi, Z.; Piperakis, M. M. (2008)
      The potential genetic hazard of pesticides to humans is of great concern, in particular in occupational and environmental settings because of their widespread use for domestic and industrial applications. In the present ...
    • MacroDevelopment of an assay to assess genotoxicity by particulate matter extract 

      Priftis A., Papikinos K., Koukoulanaki M., Kerasioti E., Stagos D., Konstantinopoulos K., Spandidos D.A., Kermenidou M., Karakitsios S., Sarigiannis D., Tsatsakis A.M., Kouretas D. (2017)
      The current study describes a method for assessing the oxidative potential of common environmental stressors (ambient air particulate matter), using a plasmid relaxation assay where the extract caused single-strand breaks, ...
    • Molecular determinants of radiosensitivity in normal and tumor tissue: A bioinformatic approach 

      Pavlopoulou A., Bagos P.G., Koutsandrea V., Georgakilas A.G. (2017)
      Although radiation therapy is a treatment of choice for cancer, a high percentage of patients develop adverse effects in normal tissue following radiotherapy, mainly, due to genetic factors. Notably, although it is established ...
    • Ochratoxin A in Slaughtered Pigs and Pork Products 

      Vlachou M., Pexara A., Solomakos N., Govaris A. (2022)
      Ochratoxin A (OTA) is a mycotoxin that is produced after the growth of several Aspergillus and Penicillium spp. in feeds or foods. OTA has been proved to possess nephrotoxic, hepatotoxic, teratogenic, neurotoxic, genotoxic, ...
    • Simulating real-life exposures to uncover possible risks to human health: A proposed consensus for a novel methodological approach 

      Tsatsakis A.M., Kouretas D., Tzatzarakis M.N., Stivaktakis P., Tsarouhas K., Golokhvast K.S., Rakitskii V.N., Tutelyan V.A., Hernandez A.F., Rezaee R., Chung G., Fenga C., Engin A.B., Neagu M., Arsene A.L., Docea A.O., Gofita E., Calina D., Taitzoglou I., Liesivuori J., Hayes A.W., Gutnikov S., Tsitsimpikou C. (2017)
      In real life, consumers are exposed to complex mixtures of chemicals via food, water and commercial products consumption. Since risk assessment usually focuses on individual compounds, the current regulatory approach doesn't ...