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Listar por tema "gene repression"

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    • Functional characterization of the hGRαT556I causing Chrousos syndrome 

      Nicolaides N.C., Skyrla E., Vlachakis D., Psarra A.-M.G., Moutsatsou P., Sertedaki A., Kossida S., Charmandari E. (2016)
      Background: Chrousos syndrome is a rare pathologic condition characterized by generalized, partial resistance of target tissues to glucocorticoids and caused by inactivating mutations of the human glucocorticoid receptor ...

    • Glucose Derivative Induced Vasculopathy in Children on Chronic Peritoneal Dialysis 

      Bartosova M., Zhang C., Schaefer B., Herzog R., Ridinger D., Damgov I., Levai E., Marinovic I., Eckert C., Romero P., Sallay P., Ujszaszi A., Unterwurzacher M., Wagner A., Hildenbrand G., Warady B.A., Schaefer F., Zarogiannis S.G., Kratochwill K., Schmitt C.P. (2021)
      RATIONALE: Patients with chronic kidney disease (CKD) have an exceedingly high cardiovascular risk; which further increases in patients on peritoneal dialysis (PD). The pathophysiological role of reactive metabolites ...

    • Mechanisms involved in the induced differentiation of leukemia cells 

      Tsiftsoglou, A. S.; Pappas, I. S.; Vizirianakis, I. S. (2003)
      Despite the remarkable progress achieved in the treatment of leukemias over the last several years, many problems (multidrug resistance [MDR], cellular heterogeneity, heterogeneous molecular abnormalities, karyotypic ...

    • Regulation of aromatase expression by hormones, drugs pesticides and environmental pollutants in canine mammary CMT-U27 cells 

      Mavridis, S. K.; Pappas, I. S. (2010)
      Aromatase, the enzyme that coverts testosterone to 17β-estradiol, has attracted attention lately because of its involvement in some forms of breast cancer in women. Studies are now undergoing on a variety of species to ...