• Hypoxia-induced Changes in SUMO Conjugation Affect Transcriptional Regulation under Low Oxygen 

      Chachami G., Stankovic-Valentin N., Karagiota A., Basagianni A., Plessmann U., Urlaub H., Melchior F., Simos G. (2019)
      Hypoxia occurs in pathological conditions, such as cancer, as a result of the imbalance between oxygen supply and consumption by proliferating cells. HIFs are critical molecular mediators of the physiological response to ...
    • IL-33/ST2 axis in organ fibrosis 

      Kotsiou O.S., Gourgoulianis K.I., Zarogiannis S.G. (2018)
      Interleukin 33 (IL-33) is highly expressed in barrier sites, acting via the suppression of tumorigenicity 2 receptor (ST2). IL-33/ST2 axis has long been known to play a pivotal role in immunity and cell homeostasis by ...