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Parcourir par sujet "cell lineage"

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    • Acquisition of optimal TFH cell function is defined by specific molecular, positional, and TCR dynamic signatures 

      Padhan K., Moysi E., Noto A., Chassiakos A., Ghneim K., Perra M.M., Shah S., Papaioannou V., Fabozzi G., Ambrozak D.R., Poultsidi A., Ioannou M., Fenwick C., Darko S., Douek D.C., Sekaly R.-P., Pantaleo G., Koup R.A., Petrovas C. (2021)
      The development of follicular helper CD4 T (TFH) cells is a dynamic process resulting in a heterogenous pool of TFH subsets. However, the cellular and molecular determinants of this heterogeneity and the possible mechanistic ...

    • Bone marrow side population cells are enriched for progenitors capable of myogenic differentiation 

      Luth, E. S.; Jun, S. J.; Wessen, M. K.; Liadaki, K.; Gussoni, E.; Kunkel, L. M. (2008)
      Although the contribution of bone marrow-derived cells to regenerating skeletal muscle has been repeatedly documented, there remains considerable debate as to whether this incorporation is exclusively a result of inflammatory ...

    • Current research and application of stem cells in the dog and cat 

      Anatolitou A.A., Sideri K.I., Prassinos N.N. (2021)
      Stem cells (SCs) are multipotent cells with differentiation and proliferation capacities in many cell lineages. The majority of literature applications are about bone marrow derived stem cells (BMSCs) and adipose derived ...

    • The Developmental Program of Murine Erythroleukemia Cells 

      Tsiftoglou, A. S.; Pappas, I. S.; Vizirianakis, I. S. (2002)
      Hematopoietic stem cells (HSCs) or early progenitors respond to external stimuli in bone marrow and differentiate into cell-restricted lineages of blood cells of limited life span. In leukemias, however, early hematopoietic ...

    • Genetic sharing with cardiovascular disease risk factors and diabetes reveals novel bone mineral density loci 

      Reppe S., Wang Y., Thompson W.K., McEvoy L.K., Schork A.J., Zuber V., LeBlanc M., Bettella F., Mills I.G., Desikan R.S., Djurovic S., Gautvik K.M., Dale A.M., Andreassen O.A., Estrada K., Styrkarsdottir U., Evangelou E., Hsu Y.-H., Duncan E.L., Ntzani E.E., Oei L., Albagha O.M.E., Amin N., Kemp J.P., Koller D.L., Li G., Liu C.-T., Minster R.L., Moayyeri A., Vandenput L., Willner D., Xiao S.-M., Yerges-Armstrong L.M., Zheng H.-F., Alonso N., Eriksson J., Kammerer C.M., Kaptoge S.K., Leo P.J., Thorleifsson G., Wilson S.G., Wilson J.F., Aalto V., Alen M., Aragaki A.K., Aspelund T., Center J.R., Dailiana Z., Duggan D.J., Garcia M., Garcia-Giralt N., Giroux S., Hallmans G., Hocking L.J., Husted L.B., Jameson K.A., Khusainova R., Kim G.S., Kooperberg C., Koromila T., Kruk M., Laaksonen M., Lacroix A.Z., Lee S.H., Leung P.C., Lewis J.R., Masi L., Mencej-Bedrac S., Nguyen T.V., Nogues X., Patel M.S., Prezelj J., Rose L.M., Scollen S., Siggeirsdottir K., Smith A.V., Svensson O., Trompet S., Trummer O., Van Schoor N.M., Woo J., Zhu K., Balcells S., Brandi M.L., Buckley B.M., Cheng S., Christiansen C., Cooper C., Dedoussis G., Ford I., Frost M., Goltzman D., González-Macías J., Kähönen M., Karlsson M., Khusnutdinova E., Koh J.-M., Kollia P., Langdahl B.L., Leslie W.D., Lips P., Ljunggren Ö., Lorenc R.S., Marc J., Mellström D., Obermayer-Pietsch B., Olmos J.M., Pettersson-Kymmer U., Reid D.M., Riancho J.A., Ridker P.M., Rousseau F., Slagboom P.E., Tang N.L.S., Urreizti R., Van Hul W., Viikari J., Zarrabeitia M.T., Aulchenko Y.S., Castano-Betancourt M., Grundberg E., Herrera L., Ingvarsson T., Johannsdottir H., Kwan T., Li R., Luben R., Medina-Gómez C., Palsson S.Th., Rotter J.I., Sigurdsson G., Van Meurs J.B.J., Verlaan D., Williams F.M.K., Wood A.R., Zhou Y., Pastinen T., Raychaudhuri S., Cauley J.A., Chasman D.I., Clark G.R., Cummings S.R., Danoy P., Dennison E.M., Eastell R., Eisman J.A., Gudnason V., Hofman A., Jackson R.D., Jones G., Jukema J.W., Khaw K.-T., Lehtimäki T., Liu Y., Lorentzon M., McCloskey E., Mitchell B.D., Nandakumar K., Nicholson G.C., Oostra B.A., Peacock M., Pols H.A.P., Prince R.L., Raitakari O., Reid I.R., Robbins J., Sambrook P.N., Sham P.C., Shuldiner A.R., Tylavsky F.A., Van Duijn C.M., Wareham N.J., Cupples L.A., Econs M.J., Evans D.M., Harris T.B., Kung A.W.C., Psaty B.M., Reeve J., Spector T.D., Streeten E.A., Zillikens M.C., Thorsteinsdottir U., Ohlsson C., Karasik D., Richards J.B., Brown M.A., Stefansson K., Uitterlinden A.G., Ralston S.H., Ioannidis J.P.A., Kiel D.P., Rivadeneira F., GEFOS Consortium (2015)
      Bone Mineral Density (BMD) is a highly heritable trait, but genome-wide association studies have identified few genetic risk factors. Epidemiological studies suggest associations between BMD and several traits and diseases, ...

    • The mast cell – Neurofibromatosis connection 

      Antonopoulos D., Tsilioni I., Balatsos N.A.A., Gourgoulianis K.I., Theoharides T.C. (2019)
      [No abstract available]

    • Pleural effusion levels of dj-1 are increased in elderly lung cancer patients with malignant pleural effusions 

      Vavougios G., Kerenidi T., Tsilioni I., Zarogiannis S.G., Gourgoulianis K.I. (2015)
      Objectives: DJ-1 is a multifunctional protein implicated in redox dependent cell fate decisions. The aim of ourstudy was to determine the pleural fluid (PF) levels of DJ-1 in malignant pleural effusions (MPEs) secondary ...

    • A Positive Regulatory Loop between a Wnt-Regulated Non-coding RNA and ASCL2 Controls Intestinal Stem Cell Fate 

      Giakountis A., Moulos P., Zarkou V., Oikonomou C., Harokopos V., Hatzigeorgiou A.G., Reczko M., Hatzis P. (2016)
      The canonical Wnt pathway plays a central role in stem cell maintenance, differentiation, and proliferation in the intestinal epithelium. Constitutive, aberrant activity of the TCF4/β-catenin transcriptional complex is the ...