Parcourir par sujet "cell compartmentalization"
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Cold shock Y-box protein-1 proteolysis autoregulates its transcriptional activities
(2013)Background: The Y-box protein-1 (YB-1) fulfills pleiotropic functions relating to gene transcription, mRNA processing, and translation. It remains elusive how YB-1 shuttling into the nuclear and cytoplasmic compartments ... -
DIANA-LncBase v3: Indexing experimentally supported miRNA targets on non-coding transcripts
(2020)DIANA-LncBase v3.0 (www.microrna.gr/LncBase) is a reference repository with experimentally supported miRNA targets on non-coding transcripts. Its third version provides approximately half a million entries, corresponding ... -
Mycobacterial immunomodulation and viral manipulation of neuronal copper efflux in the setting of sporadic Parkinson's disease: A multi – hit, outside – in hypothesis of its pathogenesis
(2020)Following Braak's hypothesis on the infectious pathogenesis of sporadic Parkinson's disease (sPD), several bacteria and viruses have been investigated as likely culprits. Recent research has focused on neuroinvasive influenza ... -
Nuclear localization of cytokeratin 8 and the O-linked N -acetylglucosamine-containing Epitope H in epithelial cells of infiltrating ductal breast carcinomas: A combination of immunogold and EDTA regressive staining methods
(2006)In a previous study, the authors have shown cytokeratin 8 (CK8) and epitope H ultrastructural localization in breast cancer cell nuclei. Epitope H contains an O-linked N -acetylglucosamine (O-GlcNAc) residue in a specific ...