• Adverse effects of androgen deprivation therapy in patients with prostate cancer: Focus on muscle and bone health 

      Bargiota A., Oeconomou A., Zachos I., Samarinas M., Pisters L.L., Tzortzis V. (2020)
      Androgen deprivation therapy (ADT) is the most effective systemic treatment for prostate cancer and can be succeeded either surgically or pharmaceutically. Both approaches lead to hypogonadism with a large variety of adverse ...
    • Assessment of bone mineral density in male patients with chronic obstructive pulmonary disease by DXA and quantitative computed tomography 

      Fountoulis G., Kerenidi T., Kokkinis C., Georgoulias P., Thriskos P., Gourgoulianis K., Fezoulidis I., Vassiou K., Vlychou M. (2016)
      The purpose of this study is to identify the prevalence of osteoporosis in male patients with chronic obstructive pulmonary disease (COPD) by dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT) ...
    • Associations between nutrition, energy expenditure and energy availability with bone mass acquisition in dance students: a 3-year longitudinal study 

      Amorim T., Freitas L., Metsios G.S., Gomes T.N., Wyon M., Flouris A.D., Maia J., Marques F., Nogueira L., Adubeiro N., Koutedakis Y. (2021)
      Summary: Three years of study showed that female and male vocational dancers displayed lower bone mass compared to controls, at forearm, lumbar spine and femoral neck. Energy intake was found to positively predict bone ...
    • Autologous (non-vascularised) fibular grafting with recombinant bone morphogenetic protein-7 for the treatment of femoral head osteonecrosis: Preliminary report 

      Papanagiotou, M.; Malizos, K. N.; Vlychou, M.; Dailiana, Z. H. (2014)
      This preliminary study evaluates a combination of bone morphogenetic protein (BMP)-7 and non-vascularised autologous fibular grafting (AFG) for the treatment of osteonecrosis of the femoral head. BMP-7/AFG combination was ...
    • Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus 

      Medina-Gomez C., Kemp J.P., Dimou N.L., Kreiner E., Chesi A., Zemel B.S., Bønnelykke K., Boer C.G., Ahluwalia T.S., Bisgaard H., Evangelou E., Heppe D.H.M., Bonewald L.F., Gorski J.P., Ghanbari M., Demissie S., Duque G., Maurano M.T., Kiel D.P., Hsu Y.-H., Van Der Eerden B.C.J., Ackert-Bicknell C., Reppe S., Gautvik K.M., Raastad T., Karasik D., Van De Peppel J., Jaddoe V.W.V., Uitterlinden A.G., Tobias J.H., Grant S.F.A., Bagos P.G., Evans D.M., Rivadeneira F. (2017)
      Bone mineral density is known to be a heritable, polygenic trait whereas genetic variants contributing to lean mass variation remain largely unknown. We estimated the shared SNP heritability and performed a bivariate GWAS ...
    • Body composition in adult patients with thalassemia major 

      Vlychou M., Alexiou E., Thriskos P., Fezoulidis I., Vassiou K. (2016)
      Objective. To assess body composition in adult male and female patients with thalassemia major by dual-energy X-ray absorptiometry (DXA) and to compare the findings with a group of healthy age-matched controls. Methods. ...
    • Bone mass of female dance students prior to professional dance training: A cross-sectional study 

      Amorim T., Metsios G.S., Wyon M., Nevill A.M., Flouris A.D., Maia J., Teixeira E., Machado J.C., Marques F., Koutedakis Y. (2017)
      Background Professional dancers are at risk of developing low bone mineral density (BMD). However, whether low BMD phenotypes already exist in pre-vocational dance students is relatively unknown. Aim To cross-sectionally ...
    • Bone mineral density and genetic markers involved in three connected pathways (focal adhesion, actin cytoskeleton regulation and cell cycle): The CUMAGAS-BMD information system 

      Zintzaras, E.; Doxani, C.; Ziogas, D. C.; Mprotsis, T.; Rodopoulou, P.; Karachalios, T. (2011)
      The focal adhesion, the actin cytoskeleton and cell-cycle are connected pathways and their genes are implicated in the pathogenesis of low BMD. Data from 211 studies that investigated the association between BMD and gene ...
    • Bone mineral density in vocational and professional ballet dancers 

      Amorim T., Koutedakis Y., Nevill A., Wyon M., Maia J., Machado J.C., Marques F., Metsios G.S., Flouris A.D., Adubeiro N., Nogueira L., Dimitriou L. (2017)
      Summary: According to existing literature, bone health in ballet dancers is controversial. We have verified that, compared to controls, young female and male vocational ballet dancers have lower bone mineral density (BMD) ...
    • Bovine colostrum supplementation improves bone metabolism in an osteoporosis-induced animal model 

      Kydonaki E.K., Freitas L., Fonseca B.M., Reguengo H., Simón C.R., Bastos A.R., Fernandes E.M., Canadas R.F., Oliveira J.M., Correlo V.M., Reis R.L., Vliora M., Gkiata P., Koutedakis Y., Ntina G., Pinto R., Carrillo A.E., Marques F., Amorim T. (2021)
      Osteoporosis is characterized by bone loss. The present study aims to investigate the effects of bovine colostrum (BC) on bone metabolism using ovariectomized (OVX) and orchidec-tomized (ORX) rat models. Twenty-seven-week-old ...
    • Bronchial Asthma and Sarcopenia: An Upcoming Potential Interaction 

      Karakousis N.D., Kotsiou O.S., Gourgoulianis K.I. (2022)
      Background: Sarcopenia seems to be an emerging health issue worldwide, concerning the progressive loss of skeletal muscle mass, accompanied by adverse outcomes. Asthma is a chronic inflammatory respiratory condition that ...
    • Comparable or higher prevalence of comorbidities in antiphospholipid syndrome vs rheumatoid arthritis: A multicenter, case-control study 

      Panopoulos S., Thomas K., Georgiopoulos G., Boumpas D., Katsiari C., Bertsias G., Drosos A.A., Boki K., Dimitroulas T., Garyfallos A., Papagoras C., Katsimbri P., Tziortziotis A., Adamichou C., Kaltsonoudis E., Argyriou E., Vosvotekas G., Sfikakis P.P., Vassilopoulos D., Tektonidou M.G. (2021)
      Objectives: Evidence on comorbidity prevalence in antiphospholipid syndrome (APS) and its difference from high comorbidity burden rheumatic diseases is limited. Herein, we compare multiple comorbidities between APS and RA. ...
    • Cortical and trabecular bone analysis of professional dancers using 3D-DXA: a case–control study 

      Freitas L., Amorim T., Humbert L., Fonollá R., Flouris A.D., Metsios G.S., Jamurtas A.Z., Koutedakis Y. (2019)
      Given the lack of relevant data, the aim of this study was to examine femur cortical and trabecular bone in female and male professional ballet dancers. 40 professional ballet dancers and 40 sex- and age-matched non-exercising ...
    • Determinants of Bone Outcomes in Adolescent Athletes at Baseline: The PRO-BONE Study 

      Vlachopoulos D., Ubago-Guisado E., Barker A.R., Metcalf B.S., Fatouros I.G., Avloniti A., Knapp K.M., Moreno L.A., Williams C.A., Gracia-Marco L. (2017)
      Purpose The determinants of areal bone mineral density (aBMD) and hip geometry estimates in adolescent athletes are poorly understood. This study aimed to identify the determinants of aBMD and hip geometry estimates in ...
    • Do Calcium Supplements Predispose to Urolithiasis? 

      Kozyrakis D., Paridis D., Karatzas A., Soukias G., Dailiana Z. (2017)
      Purpose of Review: The purpose of this study was to investigate the role of calcium supplements, with or without vitamin D, in urinary stone formation in healthy population and in osteoporotic patients as well. Moreover, ...
    • The effects of calcitonin on acute bone loss after pertrochanteric fractures. A prospective, randomised trial 

      Karachalios, T.; Lyritis, G. P.; Kaloudis, J.; Roidis, N.; Katsiri, M. (2004)
      We investigated the effect of calcitonin in the prevention of acute bone loss after a pertrochanteric fracture and its ability to reduce the incidence of further fractures in the same patient. Fifty women aged between 70 ...
    • Endocrine parameters in association with bone mineral accrual in young female vocational ballet dancers 

      Amorim T., Metsios G.S., Flouris A.D., Nevill A., Gomes T.N., Wyon M., Marques F., Nogueira L., Adubeiro N., Jamurtas A.Z., Maia J., Koutedakis Y. (2019)
      Summary: Less is known on bone mass gains in dancers involved in vocational dance training. The present study found that, as young vocational dancers progress on their professional training, their bone health remains ...
    • Endocrine resistance and epigenetic reprogramming in estrogen receptor positive breast cancer 

      Dimitrakopoulos F.-I., Kottorou A., Tzezou A. (2021)
      Despite the enormous advances during the last three decades, breast cancer continues to be the most frequent type of cancer as well as one of the most frequent cancer-related causes of death in women. Therapeutic management ...
    • Fanconi syndrome in the adulthood. The role of early diagnosis and treatment 

      Karatzas A.D., Paridis D., Kozyrakis D., Tzortzis V., Samarinas M., Dailiana Z., Karachalios T. (2017)
      [No abstract available]
    • Genetic sharing with cardiovascular disease risk factors and diabetes reveals novel bone mineral density loci 

      Reppe S., Wang Y., Thompson W.K., McEvoy L.K., Schork A.J., Zuber V., LeBlanc M., Bettella F., Mills I.G., Desikan R.S., Djurovic S., Gautvik K.M., Dale A.M., Andreassen O.A., Estrada K., Styrkarsdottir U., Evangelou E., Hsu Y.-H., Duncan E.L., Ntzani E.E., Oei L., Albagha O.M.E., Amin N., Kemp J.P., Koller D.L., Li G., Liu C.-T., Minster R.L., Moayyeri A., Vandenput L., Willner D., Xiao S.-M., Yerges-Armstrong L.M., Zheng H.-F., Alonso N., Eriksson J., Kammerer C.M., Kaptoge S.K., Leo P.J., Thorleifsson G., Wilson S.G., Wilson J.F., Aalto V., Alen M., Aragaki A.K., Aspelund T., Center J.R., Dailiana Z., Duggan D.J., Garcia M., Garcia-Giralt N., Giroux S., Hallmans G., Hocking L.J., Husted L.B., Jameson K.A., Khusainova R., Kim G.S., Kooperberg C., Koromila T., Kruk M., Laaksonen M., Lacroix A.Z., Lee S.H., Leung P.C., Lewis J.R., Masi L., Mencej-Bedrac S., Nguyen T.V., Nogues X., Patel M.S., Prezelj J., Rose L.M., Scollen S., Siggeirsdottir K., Smith A.V., Svensson O., Trompet S., Trummer O., Van Schoor N.M., Woo J., Zhu K., Balcells S., Brandi M.L., Buckley B.M., Cheng S., Christiansen C., Cooper C., Dedoussis G., Ford I., Frost M., Goltzman D., González-Macías J., Kähönen M., Karlsson M., Khusnutdinova E., Koh J.-M., Kollia P., Langdahl B.L., Leslie W.D., Lips P., Ljunggren Ö., Lorenc R.S., Marc J., Mellström D., Obermayer-Pietsch B., Olmos J.M., Pettersson-Kymmer U., Reid D.M., Riancho J.A., Ridker P.M., Rousseau F., Slagboom P.E., Tang N.L.S., Urreizti R., Van Hul W., Viikari J., Zarrabeitia M.T., Aulchenko Y.S., Castano-Betancourt M., Grundberg E., Herrera L., Ingvarsson T., Johannsdottir H., Kwan T., Li R., Luben R., Medina-Gómez C., Palsson S.Th., Rotter J.I., Sigurdsson G., Van Meurs J.B.J., Verlaan D., Williams F.M.K., Wood A.R., Zhou Y., Pastinen T., Raychaudhuri S., Cauley J.A., Chasman D.I., Clark G.R., Cummings S.R., Danoy P., Dennison E.M., Eastell R., Eisman J.A., Gudnason V., Hofman A., Jackson R.D., Jones G., Jukema J.W., Khaw K.-T., Lehtimäki T., Liu Y., Lorentzon M., McCloskey E., Mitchell B.D., Nandakumar K., Nicholson G.C., Oostra B.A., Peacock M., Pols H.A.P., Prince R.L., Raitakari O., Reid I.R., Robbins J., Sambrook P.N., Sham P.C., Shuldiner A.R., Tylavsky F.A., Van Duijn C.M., Wareham N.J., Cupples L.A., Econs M.J., Evans D.M., Harris T.B., Kung A.W.C., Psaty B.M., Reeve J., Spector T.D., Streeten E.A., Zillikens M.C., Thorsteinsdottir U., Ohlsson C., Karasik D., Richards J.B., Brown M.A., Stefansson K., Uitterlinden A.G., Ralston S.H., Ioannidis J.P.A., Kiel D.P., Rivadeneira F., GEFOS Consortium (2015)
      Bone Mineral Density (BMD) is a highly heritable trait, but genome-wide association studies have identified few genetic risk factors. Epidemiological studies suggest associations between BMD and several traits and diseases, ...