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Πλοήγηση ανά Θέμα "autoimmune liver disease"

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    • 2020 international consensus on ANCA testing beyond systemic vasculitis 

      Moiseev S., Cohen Tervaert J.W., Arimura Y., Bogdanos D.P., Csernok E., Damoiseaux J., Ferrante M., Flores-Suárez L.F., Fritzler M.J., Invernizzi P., Jayne D., Jennette J.C., Little M.A., McAdoo S.P., Novikov P., Pusey C.D., Radice A., Salama A.D., Savige J.A., Segelmark M., Shoenfeld Y., Sinico R.A., Sousa M.-J., Specks U., Terrier B., Tzioufas A.G., Vermeire S., Zhao M.-H., Bossuyt X. (2020)
      This document follows up on a 2017 revised international consensus on anti-neutrophil cytoplasm antibodies (ANCA) testing in granulomatosis with polyangiitis and microscopic polyangiitis and focuses on the clinical and ...

    • Anemia associated with autoimmune liver disease in a middle-aged female 

      Karakousis N.D., Kolonia V., Saltamavros A.D., Ntellas P., Kaligeros K. (2019)
      Autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC) can coexist as a variant syndrome of autoimmune liver disease. The case is reported of a 49-year-old woman with anemia and ascites, in whom laboratory tests ...

    • Autoantibodies to asialoglycoprotein receptor (ASGPR) in patients with autoimmune liver diseases 

      Villalta, D.; Mytilinaiou, M. G.; Elsner, M.; Hentschel, C.; Cuccato, J.; Somma, V.; Schierack, P.; Roggenbuck, D.; Bogdanos, D. P. (2015)
      Background: The liver asialoglycoprotein receptor (ASGPR) is the only organ-specific autoantigenic target in autoimmune hepatitis (AIH) patients and corresponding autoantibodies (Abs) have been suggested aiding in the ...

    • The challenges of primary biliary cholangitis: What is new and what needs to be done 

      Terziroli Beretta-Piccoli B., Mieli-Vergani G., Vergani D., Vierling J.M., Adams D., Alpini G., Banales J.M., Beuers U., Björnsson E., Bowlus C., Carbone M., Chazouillères O., Dalekos G., De Gottardi A., Harada K., Hirschfield G., Invernizzi P., Jones D., Krawitt E., Lanzavecchia A., Lian Z.-X., Ma X., Manns M., Mavilio D., Quigley E.M., Sallusto F., Shimoda S., Strazzabosco M., Swain M., Tanaka A., Trauner M., Tsuneyama K., Zigmond E., Gershwin M.E. (2019)
      Primary Biliary Cholangitis (PBC) is an uncommon, chronic, cholangiopathy of autoimmune origin and unknown etiology characterized by positive anti-mitochondrial autoantibodies (AMA), female preponderance and progression ...

    • A comprehensive analysis of antigen-specific autoimmune liver disease related autoantibodies in patients with multiple sclerosis 

      Tsouris Z., Liaskos C., Dardiotis E., Scheper T., Tsimourtou V., Meyer W., Hadjigeorgiou G., Bogdanos D.P. (2020)
      Introduction: Abnormal liver function tests are frequently seen in patients with multiple sclerosis (MS) and their origin at times is attributed to the possible co-occurrence or the de novo induction of autoimmune liver ...

    • FibroMeter scores for the assessment of liver fibrosis in patients with autoimmune liver diseases 

      Zachou K., Lygoura V., Arvaniti P., Giannoulis G., Gatselis N.K., Koukoulis G.K., Dalekos G.N. (2021)
      Introduction and Objectives: We assessed FibroMeter virus (FMvirus) and FibroMeter vibration-controlled transient elastography (FMVCTE) in 134 patients with autoimmune liver diseases [ALD, autoimmune hepatitis (AIH) and ...

    • First Results From a Propensity Matching Trial of Mycophenolate Mofetil vs. Azathioprine in Treatment-Naive AIH Patients 

      Dalekos G.N., Arvaniti P., Gatselis N.K., Samakidou A., Gabeta S., Rigopoulou E., Koukoulis G.K., Zachou K. (2022)
      Background/Aims: As previous real-world studies and meta-analyses have shown that mycophenolate mofetil (MMF) might have better efficacy than azathioprine (AZA) in autoimmune hepatitis (AIH), we conducted a propensity ...

    • The role of invariant NKT in autoimmune liver disease: Can Vitamin D Act as an Immunomodulator? 

      Smyk D.S., Mavropoulos A., Mieli-Vergani G., Vergani D., Lenzi M., Bogdanos D.P. (2018)
      Natural killer T (NKT) cells are a distinct lineage of T cells which express both the T cell receptor (TCR) and natural killer (NK) cell markers. Invariant NKT (iNKT) cells bear an invariant TCR and recognize a small variety ...

    • Second generation analysis of antinuclear antibody (ANA) by combination of screening and confirmatory testing 

      Scholz J., Grossmann K., Knütter I., Hiemann R., Sowa M., Röber N., Rödiger S., Schierack P., Reinhold D., Bogdanos D.P., Meroni P.L., Radice A., Conrad K., Roggenbuck D. (2015)
      Background: For the serological diagnosis of systemic autoimmune rheumatic diseases, a two-tier approach starting with sensitive antinuclear antibody (ANA) detection by indirect immunofluorescence (IIF) on HEp-2 cells ...

    • Smoke and autoimmunity: The fire behind the disease 

      Perricone C., Versini M., Ben-Ami D., Gertel S., Watad A., Segel M.J., Ceccarelli F., Conti F., Cantarini L., Bogdanos D.P., Antonelli A., Amital H., Valesini G., Shoenfeld Y. (2016)
      The association between smoke habit and autoimmunity has been hypothesized a long time ago. Smoke has been found to play a pathogenic role in certain autoimmune disease as it may trigger the development of autoantibodies ...

    • Support of precision medicine through risk-stratification in autoimmune liver diseases – histology, scoring systems, and non-invasive markers 

      Bossen L., Gerussi A., Lygoura V., Mells G.F., Carbone M., Invernizzi P. (2018)
      Autoimmune liver diseases (AILDs) are complex conditions, which arise from the interaction between a genetic susceptibility and unknown environmental triggers. They represent a relevant cause of liver failure and liver ...