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Sfoglia per Soggetto "Wnt pathway"

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    • Proliferation and bone marrow engraftment of AML blasts is dependent on beta-catenin signalling 

      Siapati, E. K.; Papadaki, M.; Kozaou, Z.; Rouka, E.; Michali, E.; Savvidou, I.; Gogos, D.; Kyriakou, D.; Anagnostopoulos, N. I.; Vassilopoulos, G. (2011)
      P>B-catenin is the central effector molecule of the canonical Wnt signalling pathway, which controls self-renewal of haematopoietic stem cells. Deregulation of this pathway occurs in various malignancies including myeloid ...