Now showing items 1-12 of 12

    • AGAMEMNON: an Accurate metaGenomics And MEtatranscriptoMics quaNtificatiON analysis suite 

      Skoufos G., Almodaresi F., Zakeri M., Paulson J.N., Patro R., Hatzigeorgiou A.G., Vlachos I.S. (2022)
      We introduce AGAMEMNON (https://github.com/ivlachos/agamemnon) for the acquisition of microbial abundances from shotgun metagenomics and metatranscriptomic samples, single-microbe sequencing experiments, or sequenced host ...
    • Assessment of the effects of oxamyl on the bacterial community of an agricultural soil exhibiting enhanced biodegradation 

      Gallego S., Devers-Lamrani M., Rousidou K., Karpouzas D.G., Martin-Laurent F. (2019)
      Modern agricultural practices largely rely on pesticides to protect crops against various pests and to ensure high yields. Following their application to crops a large amount of pesticides ends up in soil where they may ...
    • DIANA-LncBase v3: Indexing experimentally supported miRNA targets on non-coding transcripts 

      Karagkouni D., Paraskevopoulou M.D., Tastsoglou S., Skoufos G., Karavangeli A., Pierros V., Zacharopoulou E., Hatzigeorgiou A.G. (2020)
      DIANA-LncBase v3.0 (www.microrna.gr/LncBase) is a reference repository with experimentally supported miRNA targets on non-coding transcripts. Its third version provides approximately half a million entries, corresponding ...
    • Diana-map: Analyzing mirna from raw ngs data to quantification 

      Alexiou A., Zisis D., Kavakiotis I., Miliotis M., Koussounadis A., Karagkouni D., Hatzigeorgiou A.G. (2021)
      microRNAs (miRNAs) are small non-coding RNAs (~22 nts) that are considered central post-transcriptional regulators of gene expression and key components in many pathological conditions. Next-Generation Sequencing (NGS) ...
    • DIANA-mirExTra v2.0: Uncovering microRNAs and transcription factors with crucial roles in NGS expression data 

      Vlachos I.S., Vergoulis T., Paraskevopoulou M.D., Lykokanellos F., Georgakilas G., Georgiou P., Chatzopoulos S., Karagkouni D., Christodoulou F., Dalamagas T., Hatzigeorgiou A.G. (2016)
      Differential expression analysis (DEA) is one of the main instruments utilized for revealing molecular mechanisms in pathological and physiological conditions. DIANA-mirExTra v2.0 (http://www.microrna. gr/mirextrav2) ...
    • DIANA-TarBase v8: A decade-long collection of experimentally supported miRNA-gene interactions 

      Karagkouni D., Paraskevopoulou M.D., Chatzopoulos S., Vlachos I.S., Tastsoglou S., Kanellos I., Papadimitriou D., Kavakiotis I., Maniou S., Skoufos G., Vergoulis T., Dalamagas T., Hatzigeorgiou A.G. (2018)
      DIANA-TarBase v8 (http://www.microrna.gr/tarbase) is a reference database devoted to the indexing of experimentally supported microRNA (miRNA) targets. Its eighth version is the first database indexing >1 million entries, ...
    • First Identification and Molecular Characterization of Avian metapneumovirus Subtype B from Chickens in Greece 

      Tucciarone C.M., Andreopoulou M., Franzo G., Prentza Z., Chaligiannis I., Cecchinato M. (2017)
      Avian metapneumovirus (aMPV) is considered a major pathogen for turkeys but its impact on chicken production is still partially neglected, even though it is fully acknowledged as a primary pathogen in chickens as well. The ...
    • Identification of the abiotic stress-related transcription in little Neptune grass Cymodocea nodosa with RNA-seq 

      Malandrakis E., Dadali O., Kavouras M., Danis T., Panagiotaki P., Miliou H., Tsioli S., Orfanidis S., Küpper F.C., Exadactylos A. (2017)
      Seagrasses exhibit vital ecological roles in the marine environment. Nevertheless, the genomic resources available for seagrasses are still scarce. In the present study, the transcriptome of Cymodocea nodosa was sequenced ...
    • Manatee: detection and quantification of small non-coding RNAs from next-generation sequencing data 

      Handzlik J.E., Tastsoglou S., Vlachos I.S., Hatzigeorgiou A.G. (2020)
      Small non-coding RNAs (sncRNAs) play important roles in health and disease. Next Generation Sequencing (NGS) technologies are considered as the most powerful and versatile methodologies to explore small RNA (sRNA) ...
    • microCLIP super learning framework uncovers functional transcriptome-wide miRNA interactions 

      Paraskevopoulou M.D., Karagkouni D., Vlachos I.S., Tastsoglou S., Hatzigeorgiou A.G. (2018)
      Argonaute crosslinking and immunoprecipitation (CLIP) experiments are the most widely used high-throughput methodologies for miRNA targetome characterization. The analysis of Photoactivatable Ribonucleoside-Enhanced (PAR) ...
    • microTSS: Accurate microRNA transcription start site identification reveals a significant number of divergent pri-miRNAs 

      Georgakilas, G.; Vlachos, I. S.; Paraskevopoulou, M. D.; Yang, P.; Zhang, Y.; Economides, A. N.; Hatzigeorgiou, A. G. (2014)
      A large fraction of microRNAs (miRNAs) are derived from intergenic non-coding loci and the identification of their promoters remains 'elusive'. Here, we present microTSS, a machine-learning algorithm that provides highly ...
    • RNAcentral: A comprehensive database of non-coding RNA sequences 

      Petrov A.I., Kay S.J.E., Kalvari I., Howe K.L., Gray K.A., Bruford E.A., Kersey P.J., Cochrane G., Finn R.D., Bateman A., Kozomara A., Griffiths-Jones S., Frankish A., Zwieb C.W., Lau B.Y., Williams K.P., Chan P.P., Lowe T.M., Cannone J.J., Gutell R.R., Machnicka M.A., Bujnicki J.M., Yoshihama M., Kenmochi N., Chai B., Cole J.R., Szymanski M., Karlowski W.M., Wood V., Huala E., Berardini T.Z., Zhao Y., Chen R., Zhu W., Paraskevopoulou M.D., Vlachos I.S., Hatzigeorgiou A.G., Ma L., Zhang Z., Puetz J., Stadler P.F., McDonald D., Basu S., Fey P., Engel S.R., Cherry J.M., Volders P.-J., Mestdagh P., Wower J., Clark M., Quek X.C., Dinger M.E., The RNAcentral Consortium (2017)
      RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNA resources and provides a single entry point for accessing ncRNA sequences of all ncRNA types from all organisms. Since ...