Listar por tema "SMOOTH-MUSCLE-CELLS"
Mostrando ítems 1-12 de 12
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Arginase type I as a marker of coronary heart disease in hemodialysis patients
(2011)Cardiovascular disease, and mainly coronary heart disease (CHD), is the leading cause of death in hemodialysis (HD) patients. Non-traditional risk factors may play an important role in this population. Arginase is known ... -
Clinical implications for Vascular Endothelial Growth Factor in the lung: friend or foe?
(2006)Vascular endothelial growth factor (VEGF) is a potent mediator of angiogenesis which has multiple effects in lung development and physiology. VEGF is expressed in several parts of the lung and the pleura while it has been ... -
CX3CR1 receptor is up-regulated in monocytes of coronary artery diseased patients: Impact of pre-inflammatory stimuli and renin-angiotensin system modulators
(2007)Fractalkine/CX3CR1 pathway is considered a major modulator of atherosclerosis. In the present study, expression of CX3CR1 on PBMCs/monocytes of healthy individuals and coronary artery diseased patients was initially assessed ... -
The flavonoid quercetin induces hypoxia-inducible factor-1 alpha (HIF-1 alpha) and inhibits cell proliferation by depleting intracellular iron
(2007)Quercetin, a flavonoid with anti- oxidant, metal chelating, kinase modulating and anti- proliferative properties, can induce hypoxia- inducible factor-1 alpha (HIF-1 alpha) in normoxia, but its mechanism of action has not ... -
Glycosaminoglycans as Key Molecules in Atherosclerosis: The Role of Versican and Hyaluronan
(2010)Cardiovascular disease is the largest cause of death in Western societies and it primarily results from atherosclerosis of large and medium-sized vessels. Atherosclerosis leads to myocardial infarction, when it occurs in ... -
In vitro responsiveness of human post-menopausal myometrium to endothelin-1 and ovarian steroids
(2005)It has been shown in vitro that endothelin 1 (ET1) differentially affects the human myometrial contractility according to the hormonal profile of women. Our purpose was to test the hypothesis that ovarian steroids influence ... -
Increased soluble E-selectin levels in type 2 diabetic patients with peripheral arterial disease
(2004)Aim. Abnormal endothelial function is well known in patients with type 2 diabetes mellitus; and thought to induce macroangiopathy. Increased levels of adhesion molecules have been found in type 2 diabetic patients and it ... -
MgcRacGAP interacts with HIF-1 alpha and regulates its transcriptional activity
(2007)HIF-1 alpha is the inducible subunit of the dimeric transcription factor HIF-1 (Hypoxia Inducible Factor 1). It is induced by hypoxia and hypoxia-mimetics in most cell types, as well as non-hypoxic signals such as growth ... -
Osteoprotegerin as a Marker of Atherosclerosis in Diabetic Patients
(2013)Atherosclerosis is the principal cause of cardiovascular disease (CVD) and has many risk factors, among which is diabetes. Osteoprotegerin (OPG) is a soluble glycoprotein, involved in bone metabolism. OPG is also found in ... -
Protein and mRNA expression levels of VEGF-A and TGF-B1 in different types of human coronary atherosclerotic lesions
(2005)It is well documented that inflammation plays a major role in the establishment and progression of atherosclerosis. Endothelial cells, vascular smooth muscle cells and m onocytes/macrophages are involved in this process ... -
Resting tension affects eNOS activity in a calcium- dependent way in airways
(2007)The alteration of resting tension (RT) from 0.5 g to 2.5 g increased significantly airway smooth muscle contractions induced by acetylcholine (ACh) in rabbit trachea. The decrease in extracellular calcium concentration ...