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Auflistung Nach Schlagwort "Molecular Sequence Annotation"

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    • DIANA-LncBase v3: Indexing experimentally supported miRNA targets on non-coding transcripts 

      Karagkouni D., Paraskevopoulou M.D., Tastsoglou S., Skoufos G., Karavangeli A., Pierros V., Zacharopoulou E., Hatzigeorgiou A.G. (2020)
      DIANA-LncBase v3.0 (www.microrna.gr/LncBase) is a reference repository with experimentally supported miRNA targets on non-coding transcripts. Its third version provides approximately half a million entries, corresponding ...

    • DIANA-mirExTra v2.0: Uncovering microRNAs and transcription factors with crucial roles in NGS expression data 

      Vlachos I.S., Vergoulis T., Paraskevopoulou M.D., Lykokanellos F., Georgakilas G., Georgiou P., Chatzopoulos S., Karagkouni D., Christodoulou F., Dalamagas T., Hatzigeorgiou A.G. (2016)
      Differential expression analysis (DEA) is one of the main instruments utilized for revealing molecular mechanisms in pathological and physiological conditions. DIANA-mirExTra v2.0 (http://www.microrna. gr/mirextrav2) ...

    • DIANA-miRGen v4: Indexing promoters and regulators for more than 1500 microRNAs 

      Perdikopanis N., Georgakilas G.K., Grigoriadis D., Pierros V., Kavakiotis I., Alexiou P., Hatzigeorgiou A. (2021)
      Deregulation of microRNA (miRNA) expression plays a critical role in the transition from a physiological to a pathological state. The accurate miRNA promoter identification in multiple cell types is a fundamental endeavor ...

    • Manatee: detection and quantification of small non-coding RNAs from next-generation sequencing data 

      Handzlik J.E., Tastsoglou S., Vlachos I.S., Hatzigeorgiou A.G. (2020)
      Small non-coding RNAs (sncRNAs) play important roles in health and disease. Next Generation Sequencing (NGS) technologies are considered as the most powerful and versatile methodologies to explore small RNA (sRNA) ...

    • Meta-analysis and bioinformatics detection of susceptibility genes in diabetic nephropathy 

      Tziastoudi M., Cholevas C., Theoharides T.C., Stefanidis I. (2022)
      The latest meta-analysis of genome-wide linkage studies (GWLS) identified nine cytogenetic locations suggestive of a linkage with diabetic nephropathy (DN) due to type 1 diabetes mellitus (T1DM) and seven locations due to ...

    • The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species 

      Papanicolaou A., Schetelig M.F., Arensburger P., Atkinson P.W., Benoit J.B., Bourtzis K., Castañera P., Cavanaugh J.P., Chao H., Childers C., Curril I., Dinh H., Doddapaneni H.V., Dolan A., Dugan S., Friedrich M., Gasperi G., Geib S., Georgakilas G., Gibbs R.A., Giers S.D., Gomulski L.M., González-Guzmán M., Guillem-Amat A., Han Y., Hatzigeorgiou A.G., Hernández-Crespo P., Hughes D.S.T., Jones J.W., Karagkouni D., Koskinioti P., Lee S.L., Malacrida A.R., Manni M., Mathiopoulos K., Meccariello A., Murali S.C., Murphy T.D., Muzny D.M., Oberhofer G., Ortego F., Paraskevopoulou M.D., Poelchau M., Qu J., Reczko M., Robertson H.M., Rosendale A.J., Rosselot A.E., Saccone G., Salvemini M., Savini G., Schreiner P., Scolari F., Siciliano P., Sim S.B., Tsiamis G., Ureña E., Vlachos I.S., Werren J.H., Wimmer E.A., Worley K.C., Zacharopoulou A., Richards S., Handler A.M. (2016)
      Background: The Mediterranean fruit fly (medfly), Ceratitis capitata, is a major destructive insect pest due to its broad host range, which includes hundreds of fruits and vegetables. It exhibits a unique ability to invade ...