• Acute Liver Failure 

      Doulberis M., Kotronis G., Gialamprinou D., Özgüler O., Exadaktylos A.K., Oikonomou V., Katsinelos P., Romiopoulos I., Polyzos S.A., Tzivras D., Deretzi G., Dardiotis E., Kountouras J. (2019)
      Acute liver failure is a rare hepatic emergent situation that affects primarily young people and has often a catastrophic or even fatal outcome. Definition of acute liver failure has not reached a universal consensus and ...
    • Clinical and virological heterogeneity of hepatitis delta in different regions world-wide: The Hepatitis Delta International Network (HDIN) 

      Wranke A., Pinheiro Borzacov L.M., Parana R., Lobato C., Hamid S., Ceausu E., Dalekos G.N., Rizzetto M., Turcanu A., Niro G.A., Lubna F., Abbas M., Ingiliz P., Buti M., Ferenci P., Vanwolleghem T., Hayden T., Dashdorj N., Motoc A., Cornberg M., Abbas Z., Yurdaydin C., Manns M.P., Wedemeyer H., Hardtke S., Serrano B., Wöbse M., Heidrich B., Muche M., Gatselis N., Zachou K., Ho E., Smedile A., Fontana R., Gish R., Obretin D., Stern R., the Hepatitis Delta International Network (2018)
      Background & Aims: Chronic hepatitis D (delta) is a major global health burden. Clinical and virological characteristics of patients with hepatitis D virus (HDV) infection and treatment approaches in different regions ...
    • Effects of Age and Sex of Response to Ursodeoxycholic Acid and Transplant-free Survival in Patients With Primary Biliary Cholangitis 

      Cheung A.C., Lammers W.J., Murillo Perez C.F., van Buuren H.R., Gulamhusein A., Trivedi P.J., Lazaridis K.N., Ponsioen C.Y., Floreani A., Hirschfield G.M., Corpechot C., Mayo M.J., Invernizzi P., Battezzati P.M., Parés A., Nevens F., Thorburn D., Mason A.L., Carbone M., Kowdley K.V., Bruns T., Dalekos G.N., Gatselis N.K., Verhelst X., Lindor K.D., Lleo A., Poupon R., Janssen H.L.A., Hansen B.E., Global PBC Study Group (2019)
      Background & Aims: Primary biliary cholangitis (PBC) predominantly affects middle-aged women; there are few data on disease phenotypes and outcomes of PBC in men and younger patients. We investigated whether differences ...
    • The frequency of central nervous system complications in the Cypriot cohort of ATTRV30M neuropathy transplanted patients 

      Dardiotis E., Andreou S., Aloizou A.-M., Panayiotou E., Siokas V., Ioannou M.N., Vounou E., Christodoulou K., Tanteles G.A., Michaelides D., Kyriakides T. (2020)
      Background: Hereditary transthyretin amyloidosis (ATTR) is a hereditary, sensorimotor and autonomic neuropathy caused by deposits of mutated transthyretin (TTR). The commonest TTR mutation is V30M (ATTRV30M) with patients ...
    • Geoepidemiology, clinical manifestations and outcome of primary biliary cholangitis in Greece 

      Gatselis N.K., Zachou K., Lygoura V., Azariadis K., Arvaniti P., Spyrou E., Papadamou G., Koukoulis G.K., Dalekos G.N., Rigopoulou E.I. (2017)
      Background & aims Primary biliary cholangitis (PBC) is a disease with rising prevalence and considerable geographical variation. To describe the prevalence, spatial and time distribution, baseline characteristics, response ...
    • Liver Regeneration by Hematopoietic Stem Cells: Have We Reached the End of the Road? 

      Siapati E.K., Roubelakis M.G., Vassilopoulos G. (2022)
      The liver is the organ with the highest regenerative capacity in the human body. However, various insults, including viral infections, alcohol or drug abuse, and metabolic overload, may cause chronic inflammation and ...
    • Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis 

      Weismüller T.J., Strassburg C.P., Trivedi P.J., Hirschfield G.M., Trivedi P.J., Bergquist A., Said K., Imam M., Lazaridis K.N., Juran B.D., Cheung A., Lindor K.D., Weismüller T.J., Lenzen H., Manns M.P., Ponsioen C.Y., Beuers U., Holm K., Naess S., Karlsen T.H., Schrumpf E., Boberg K.M., Gotthardt D., Rupp C., Färkkilä M.A., Jokelainen K., Marschall H.-U., Benito de Valle M., Thorburn D., Saffioti F., Weersma R.K., Fevery J., Mueller T., Chazouillères O., Schulze K., Schramm C., Almer S., Pereira S.P., Levy C., Mason A., Bowlus C.L., Floreani A., Halilbasic E., Trauner M., Yimam K.K., Milkiewicz P., Milkiewicz P., Huynh D.K., Pares A., Manser C.N., Dalekos G.N., Eksteen B., Invernizzi P., Berg C.P., Kirchner G.I., Sarrazin C., Zimmer V., Fabris L., Braun F., Marzioni M., Schramm C., Chapman R.W., Chapman R.W., Lindor K.D., Imam M., Lindor K.D., Naess S., Karlsen T.H., Schrumpf E., Boberg K.M., Hansen B.E., Hansen B.E., Hansen B.E., on behalf of the, International PSC Study Group (2017)
      Background & Aims Primary sclerosing cholangitis (PSC) is an orphan hepatobiliary disorder associated with inflammatory bowel disease (IBD). We aimed to estimate the risk of disease progression based on distinct clinical ...
    • Similar risk of hepatocellular carcinoma during long-term entecavir or tenofovir therapy in Caucasian patients with chronic hepatitis B 

      Papatheodoridis G.V., Dalekos G.N., Idilman R., Sypsa V., Van Boemmel F., Buti M., Calleja J.L., Goulis J., Manolakopoulos S., Loglio A., Papatheodoridi M., Gatselis N., Veelken R., Lopez-Gomez M., Hansen B.E., Savvidou S., Kourikou A., Vlachogiannakos J., Galanis K., Yurdaydin C., Esteban R., Janssen H.L.A., Berg T., Lampertico P. (2020)
      Background & Aims: A recent study in Asian patients with chronic hepatitis B (CHB) reported that the incidence of hepatocellular carcinoma (HCC) was lower in patients treated with tenofovir disoproxil fumarate (TDF) than ...