Parcourir par sujet "Leptin"
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Accuracy of leptin serum level in diagnosing ventilator-associated pneumonia: a case-control study
(2014)Background. Undernutrition causes a reduction of body-fat mass and a decrease in the circulating concentration of leptin which impairs the production of proinflammatory cytokines and increases the incidence of infectious ... -
Adipokines as mediators of endothelial function and atherosclerosis
(2013)For many decades, adipose tissue was considered as an inactive body compartment that was only used as an energy store. During the recent years, an increasing amount of data has revealed that adipose tissue is a major ... -
The Association of Metabolic Syndrome with Adipose Tissue Hormones and Insulin Resistance in Patients with COPD without Co-morbidities
(2011)Chronic obstructive pulmonary disease (COPD) and metabolic syndrome represent common causes of morbidity and mortality in ageing populations. The effect of the co-existence of COPD and metabolic syndrome on adipose tissue ... -
The associations between dairy product consumption and biomarkers of inflammation, adipocytokines, and oxidative stress in children: A cross-sectional study
(2020)The association between dairy product consumption and biomarkers of inflammation, adipocytokines, and oxidative stress is poorly studied in children. Therefore, these associations were examined in a representative subsample ... -
Associations between ghrelin and leptin and neural food cue reactivity in a fasted and sated state
(2021)Food cue exposure can trigger eating. Food cue reactivity (FCR) is a conditioned response to food cues and includes physiological responses and activation of reward-related brain areas. FCR can be affected by hunger and ... -
Clinical significance of serum adipokines levels in lung cancer
(2013)Adipokines have a significant effect on metabolism, immunoinflammatory responses as well as on carcinogenesis; therefore, we aimed at evaluating their potential predictive and prognostic significance in lung cancer. Eighty ... -
Complications of chronic peritoneal dialysis: The role of leptin
(2011)The use of peritoneal dialysis for patients with end stage renal disease is not widespread, mainly because of the complications of repeated peritoneal dialysis, such as peritonitis and peritoneal fibrosis. Leptin is a 16 ... -
Consequences of protein supplementation for anorexia, expression of immunity and plasma leptin concentrations in parasitized ewes of two breeds
(2009)The periparturient relaxation of immunity (PPRI) against parasites in ewes has a nutritional basis. We investigated whether ewes experience a reduction in food intake (anorexia) during PPRI and if the magnitude of anorexia ... -
Differential expression of leptin and leptin's receptor isoform (Ob-Rb) mRNA between advanced and minimally affected osteoarthritic cartilage; effect on cartilage metabolism
(2007)Objective: To investigate leptin's effect on cartilage metabolism and the pathophysiology of osteoarthritis (OA). Methods: Messenger RNA (mRNA) expression and protein levels of leptin and leptin's receptor isoforms were ... -
Effects of smoking cessation on serum leptin and adiponectin levels
(2015)Background: Evidence on the association of leptin and adiponectin and smoking is limited and discordant. Leptin and adiponectin represent the most abundant adipokines in human plasma that play crucial roles in the ... -
Growth hormone, insulin-like growth factor I, and leptin interaction in human cultured lutein granulosa cells steroidogenesis
(2008)Objective: To investigate the effect of leptin on the actions of growth hormone (GH) and insulin-like growth factor-I (IGF-I) in ovarian steroidogenesis in vitro. Design: In vitro cell culture study. Setting: Research ... -
Interrelations among the adipocytokines leptin and adiponectin, oxidative stress and aseptic inflammation markers in pre- and early-pubertal normal-weight and obese boys
(2017)Purpose: Presumed interrelationships among deleterious aspects of adipose tissue metabolism, inflammation, and cellular oxidative stress could be influenced by pubertal hormonal changes. They were investigated in pre- and ... -
Leptin concentrations in normal women following bilateral ovariectomy
(1999)To study the relationships between gonadal steroids and leptin, 20 women with normal cycles were investigated during the postoperative period following a laparotomy. Fourteen women underwent bilateral ovariectomy plus total ... -
Leptin in pregnancy
(2002)Leptin is a 16-kDa polypeptide, encoded in humans by the LEP gene. This protein is probably involved in the regulation of ovarian function, oocyte maturation and embryo development, and in the implantation process. During ... -
Leptin-depended NLRP3 inflammasome activation in osteoarthritic chondrocytes is mediated by ROS
(2022)Leptin and ROS are implicated in the regulation of inflammatory pathways including NLRP3-inflammasome. We investigated the functional link between leptin, ROS and NLRP3-inflammasome formation/activation in osteoarthritis ... -
A Modified Mediterranean Diet Improves Fasting and Postprandial Glucoregulation in Adults with Overweight and Obesity: A Pilot Study
(2022)The ideal lifestyle intervention to battle both obesity and diabetes is currently unknown. The aim of this pilot uncontrolled intervention trial was to assess the effect of a modified Mediterranean diet (MedDiet) on weight ... -
Relation between leptin and cortisol values in umbilical vessels at normal vaginal delivery
(2004)To study the role of various hormones in the control of fetal leptin secretion during labour, 33 pregnant women with normal singleton term pregnancy were recruited. At the time of spontaneous vaginal delivery, a venous ... -
Synergy of leptin/STAT3 with HER2 receptor induces tamoxifen resistance in breast cancer cells through regulation of apoptosis-related genes
(2015)Tamoxifen is a major treatment modality for estrogen receptor positive breast cancer, but the occurrence of resistance remains a problem. Recently, obesity-related leptin has been found to interfere with tamoxifen in breast ... -
Unraveling the link between leptin, ghrelin and different types of colitis
(2011)Leptin and ghrelin are hormones with a tight inverse functional connection. Their inverse association is observed not only in the modulation of metabolism but also in the interaction with the immune system. A large number ...