Πλοήγηση ανά Θέμα "ENDOTHELIAL-CELLS"

Bortezomib represses HIF-1 alpha protein expression and nuclear accumulation by inhibiting both PI3K/Akt/TOR and MAPK pathways in prostate cancer cells

Befani, C. D.; Vlachostergios, P. J.; Hatzidaki, E.; Patrikidou, A.; Bonanou, S.; Simos, G.; Papandreou, C. N.; Liakos, P. (2012)

Bortezomib represents the first proteasome inhibitor (PI) with demonstrated antitumor activity in the clinical setting, particularly for treatment of hematological malignancies. At the preclinical level, its action is shown ...

Circulating adhesion molecules levels in type 2 diabetes mellitus and hypertension

Boulbou, M. S.; Koukoulis, G. N.; Makri, E. D.; Petinaki, E. A.; Gourgoulianis, K. I.; Germenis, A. E. (2005)

Background: Risk factors for atherosclerosis such as hypertension, type 2 diabetes, obesity and dyslipidemia affect endothelial function and stimulate adhesion molecules expression. The aim of the study was to examine ...

The effect of homocysteine on the clinical outcomes of ventilated patients with severe sepsis

Tsantes, A.; Tsangaris, I.; Nikolopoulos, G.; Bagos, P.; Kopterides, P.; Antonakos, G.; Dimopoulou, I.; Vrioni, G.; Kapsimali, V.; Dima, K.; Armaganidis, A.; Travlou, A. (2010)

Background. There is considerable evidence that elevated plasma homocysteine levels are associated with a prothrombotic milieu, whereas activation of the coagulation cascade is an important component of the pathogenesis ...

The Effect of Plasma Homocysteine Levels on Clinical Outcomes of Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome

Tsangaris, I.; Tsantes, A.; Bagos, P.; Nikolopoulos, G.; Kroupis, C.; Kopterides, P.; Dimopoulou, I.; Orfanos, S.; Kardoulaki, A.; Chideriotis, S.; Travlou, A.; Armaganidis, A. (2009)

Background: Several reports have shown that homocysteine promotes thrombosis by disturbing the procoagulant-anticoagulant balance, whereas alterations in coagulation and fibrinolysis have been suggested as important ...

Electrophysiological and mechanical properties of isolated rabbit heart papillary muscles and their correlation with nitric oxide (NO) and oxygen free radicals in hypovolemic shock blood plasma

Chaniotis, D. I.; Deliconstantinos, G.; Lymberi, M.; Poyatzi, A.; Stavridis, J. C.; Molyvdas, P. A. (1997)

We investigated the electrophysiological and contractile responses of isolated rabbit heart papillary muscles, to plasma from the blood of rabbits suffering severe hypovolemic shock (SP) and compared the production of ...

Expression of heregulin in human coronary atherosclerotic lesions

Panutsopulos, D.; Arvanitis, D. L.; Tsatsanis, C.; Papalambros, E.; Sigala, F.; Spandidos, D. A. (2005)

Background: Endothelial cells, monocytes/macrophages, and vascular smooth muscle cells contribute to the establishment and progression of atherosclerotic lesions by expressing growth and inflammatory factors. The aim of ...

Fibrinolytic/hemostatic variables in arterial hypertension: Response to treatment with irbesartan or atenolol

Makris, T. K.; Stavroulakis, G. A.; Krespi, P. G.; Hatzizacharias, A. N.; Triposkiadis, F. K.; Tsoukala, C. G.; Votteas, V. V.; Kyriakidis, M. K. (2000)

Essential hypertension is often accompanied by abnormalities of the coagulation/fibrinolytic system, predisposing to a procoagulant state. The aim of the present study was to compare the effects of atenolol (beta(1)-blocker ...

Helicobacter pylori neutrophil activating protein as target for new drugs against H. pylori inflammation

Choli-Papadopoulou, T.; Kottakis, F.; Papadopoulos, G.; Pendas, S. (2011)

Helicobacter pylori (H. pylon) infection is among the most common human infections and the major risk factor for peptic ulcer disease and gastric cancer. Within this work we present the implication of C-terminal region of ...

Hemodialysis procedure does not affect the levels of sICAM-1 and sVCAM-1 in patients with end stage renal disease

Liakopoulos, V.; Eleftheriadis, T.; Kyropoulos, T.; Voliotis, G.; Potamianos, S.; Zengos, N.; Stefanidis, I.; Heintz, B. (2005)

Atherosclerosis is by far the leading cause of mortality and morbidity in patients with end stage renal disease undergoing chronic hemodialysis (HD). Vascular endothelial cell adhesion molecules like the intercellular ...

Interleukin-6 and matrix metalloproteinase expression in the subretinal fluid during proliferative vitreoretinopathy: Correlation with extent, duration of RRD and PVR grade

Symeonidis, C.; Papakonstantinou, E.; Androudi, S.; Tsaousis, K. T.; Tsinopoulos, I.; Brazitikos, P.; Karakiulakis, G.; Diza, E.; Dimitrakos, S. A. (2012)

Purpose: To investigate interleukin (IL)-6 protein levels in the subretinal fluid (SRF) of patients with rhegmatogenous retinal detachment (RRD) complicated by proliferative vitreoretinopathy (PVR); to correlate the IL-6 ...