• Adrenomedullin optimises mortality prediction in COPD patients 

      Brusse-Keizer, M.; Zuur-Telgen, M.; van der Palen, J.; VanderValk, P.; Kerstjens, H.; Boersma, W.; Blasi, F.; Kostikas, K.; Milenkovic, B.; Tamm, M.; Stolz, D. (2015)
      Background: Current multicomponent scores that predict mortality in COPD patients might underestimate the systemic component of COPD. Therefore, we evaluated the accuracy of circulating levels of proadrenomedullin (MR-proADM) ...
    • Associations between BODE Index and Systemic Inflammatory Biomarkers in COPD 

      Gaki, E.; Kontogianni, K.; Papaioannou, A. I.; Bakakos, P.; Gourgoulianis, K. I.; Kostikas, K.; Alchanatis, M.; Papiris, S.; Loukides, S. (2011)
      Background: COPD is a multicomponent disease and systemic inflammation represents one of the possible mechanisms responsible for its systemic manifestations, including skeletal muscle weakness and cachexia. Fat-free mass ...
    • Fetuin-A is Associated with Disease Severity and Exacerbation Frequency in Patients with COPD 

      Minas, M.; Mystridou, P.; Georgoulias, P.; Pournaras, S.; Kostikas, K.; Gourgoulianis, K. I. (2013)
      Fetuin-A is a liver protein that may serve as an inhibitor of systemic inflammation in humans. In the present study we assessed the levels of fetuin-A in COPD patients in stable condition and on exacerbation in an attempt ...
    • Noninvasive Ventilation in Chronic Respiratory Failure: Effects on Quality of Life 

      Tsolaki, V.; Pastaka, C.; Kostikas, K.; Karetsi, E.; Dimoulis, A.; Zikiri, A.; Koutsokera, A.; Gourgoulianis, K. I. (2011)
      Background: Noninvasive ventilation (NIV) has been found to be an essential technique to treat chronic respiratory failure (CRF) resulting from restrictive thoracic disorders (RTD). The last decades were characterized by ...