• CpG Island Methylation Patterns in Relapsing-Remitting Multiple Sclerosis 

      Sokratous M., Dardiotis E., Bellou E., Tsouris Z., Michalopoulou A., Dardioti M., Siokas V., Rikos D., Tsatsakis A., Kovatsi L., Bogdanos D.P., Hadjigeorgiou G.M. (2018)
      DNA methylation may predispose to multiple sclerosis (MS), as aberrant methylation in the promoter regions across the genome seems to underlie several processes of MS. We have currently determined the methylation status ...
    • DNA methylation regulates miR-140-5p and miR-146a expression in osteoarthritis 

      Papathanasiou I., Trachana V., Mourmoura E., Tsezou A. (2019)
      Aims: Previous studies have demonstrated that transcriptional silencing of miRNAs due to DNA hypermethylation is associated with different pathologies. It has also been reported that abnormal expression of miR-140-5p and ...
    • Endocrine resistance and epigenetic reprogramming in estrogen receptor positive breast cancer 

      Dimitrakopoulos F.-I., Kottorou A., Tzezou A. (2021)
      Despite the enormous advances during the last three decades, breast cancer continues to be the most frequent type of cancer as well as one of the most frequent cancer-related causes of death in women. Therapeutic management ...