Πλοήγηση ανά Θέμα "Chronic myeloid leukemia"

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Methylation status of RASSF1A in patients with chronic myeloid leukemia

Avramouli, A.; Tsochas, S.; Mandala, E.; Katodritou, E.; Ioannou, M.; Ritis, K.; Speletas, M. (2009)

RASSF1A, a key cell cycle related gene, is expressed in all hematopoietic cells, it is implicated in ras signaling pathway and its promoter hypermethylation is observed in a wide variety of solid tumors. Till now, RASSF1A ...
Survivin isoform expression patterns in CML patients correlate with resistance to imatinib and progression, but do not trigger cytolytic responses

Speletas, M.; Argentou, N.; Karanikas, V.; Gramoustianou, E. S.; Mandala, E.; Braimi, M.; Matsouka, P.; Ritis, K.; Germenis, A. E. (2011)

Tyrosine-kinase inhibitors are very effective in patients with CML, but in most cases the disease relapses after their discontinuation. As a result, novel approaches should be considered, such as anti-survivin treatment ...