Πλοήγηση ανά Θέμα "Case-Control Studies"

The -938C>A polymorphism in MYD88 is associated with susceptibility to tuberculosis: A pilot study

Aggelou K., Siapati E.K., Gerogianni I., Daniil Z., Gourgoulianis K., Ntanos I., Simantirakis E., Zintzaras E., Mollaki V., Vassilopoulos G. (2016)

Introduction. Tuberculosis (TB) is a major disease worldwide, caused by Mycobacterium tuberculosis (MTB) infection.The Toll- Like Receptor (TLR) pathway plays a crucial role in the recognition of MTB. Aim. The present study ...

Acoustic and Perceived Measurements Certifying Tango as Voice Treatment Method

Tafiadis D., Kosma E.I., Chronopoulos S.K., Papadopoulos A., Toki E.I., Vassiliki S., Ziavra N. (2018)

Voice disorders are affecting everyday life in many levels, and their prevalence has been studied extensively in certain and general populations. Notably, several factors have a cohesive influence on voice disorders and ...

Analysis of ADORA2A rs5760423 and CYP1A2 rs762551 Genetic Variants in Patients with Alzheimer’s Disease

Siokas V., Mouliou D.S., Liampas I., Aloizou A.-M., Folia V., Zoupa E., Papadimitriou A., Lavdas E., Bogdanos D.P., Dardiotis E. (2022)

Various studies have been conducted, exploring the genetic susceptibility of Alzheimer’s disease (AD). Adenosine receptor subtype A2a (ADORA2A) and cytochrome P450 1A2 (CYP1A2) are implicated in pathways such as oxidative ...

Anti-MCV antibodies predict radiographic progression in Greek patients with very early (<3 months duration) rheumatoid arthritis

Barouta G., Katsiari C.G., Alexiou I., Liaskos C., Varna A., Bogdanos D.P., Germenis A.E., Sakkas L.I. (2017)

This study aimed to assess the diagnostic and prognostic value of anti-mutated citrullinated vimentin (MCV) antibodies in very early rheumatoid arthritis (VERA) and in established rheumatoid arthritis (RA). Seventy-one ...

Assessment of health related quality of life in polish patients with primary biliary cirrhosis

Raszeja-Wyszomirska J., Wunsch E., Krawczyk M., Rigopoulou E.I., Kostrzewa K., Norman G.L., Bogdanos D.P., Milkiewicz P. (2016)

Background Most patients with primary biliary cirrhosis (PBC) have impaired health related quality of life (HRQoL), as assessed by PBC-specific HRQoL (PBC-40) and generic (SF-36) questionnaires. Data on the applicability ...

Assessment of TREM2 rs75932628 variant’s association with Parkinson’s disease in a Greek population and Meta-analysis of current data

Dardiotis E., Rikos D., Siokas V., Aloizou A.-M., Tsouris Z., Sakalakis E., Brotis A.G., Bogdanos D.P., Hadjigeorgiou G.M. (2021)

Background: Α number of genetic variants are considered to confer susceptibility to Parkinson’s disease (PD). Rs75392628 (R47H), a rare variant of TREM2 gene, has been linked to PD, although its role on PD remains conflicting. ...

Association analysis of FTO gene polymorphisms with obesity in Greek adults

Goutzelas Y., Kotsa K., Vasilopoulos Y., Tsekmekidou X., Stamatis C., Yovos J.G., Sarafidou T., Mamuris Z. (2017)

Nowadays, obesity is the greatest scourge worldwide, particularly for the developed countries and is a huge burden for the public health. Over the past decade, GWAS have revealed a number of genes associated with obesity. ...

Association between heavy precipitation events and waterborne outbreaks in four Nordic countries, 1992-2012

Herrador B.G., De Blasio B.F., Carlander A., Ethelberg S., Hygen H.O., Kuusi M., Lund V., Löfdahl M., MacDonald E., Martinez-Urtaza J., Nichols G., Schönning C., Sudre B., Trönnberg L., Vold L., Semenza J.C., Nygård K. (2016)

We conducted a matched case-control study to examine the association between heavy precipitation events and waterborne outbreaks (WBOs) by linking epidemiological registries and meteorological data between 1992 and 2012 ...

Association of IL-10 gene promoter polymorphisms with food allergy susceptibility and serum IL-10 level in a pediatric Caucasian population

Nedelkopoulou N., Taparkou A., Raftopoulou S., Gidaris D., Xinias I., Mavroudi A., Dhawan A., Farmaki E. (2021)

Background: Interleukin 10 has been shown to play a critical role in the regulation of the immune responses in allergic diseases. Aim: To investigate if genetic polymorphisms in the promoter region of the IL-10 gene are ...

Association of maternal Toll-like receptor-4 alleles with susceptibility to early-onset preeclampsia in central Greece

Vamvakopoulou D.N., Satra M., Fegga A., Kourti M., Sidiropoulos A., Daponte A., Gounaris A., Syrogianopoulos G., Vamvakopoulos N.C., Sotiriou S. (2019)

Introduction: Altered maternal inflammatory responses may play a role in the development of hypertensive disorders of pregnancy like preeclampsia, its more severe early-onset form and intrauterine growth restriction. We ...

Association of the leptin gene with knee osteoarthritis susceptibility in a Han Chinese population: A case-control study

Qin, J.; Shi, D.; Dai, J.; Zhu, L.; Tsezou, A.; Jiang, Q. (2010)

Previous studies have suggested that leptin works as a key regulator in the pathogenesis of osteoarthritis (OA), and genetic factors modulate OA. This study assessed the contribution of leptin gene (LEP) polymorphism(s) ...

Association of α-synuclein Rep1 polymorphism and Parkinson's disease: Influence of Rep1 on age at onset

Hadjigeorgiou, G. H.; Xiromerisiou, G.; Gourbali, V.; Aggelakis, K.; Scarmeas, N.; Papadimitriou, A.; Singleton, A. (2006)

The α-synuclein Rep1 polymorphism was studied in patients and controls in an ethnic Greek population. There was an association of allele 2 with risk of Parkinson's disease (PD; adjusted odd ratio = 3.25; 95% CI = 1.80-5.87). ...

Autoantibodies in patients with systemic sclerosis and cancer: A case-control study

Derk, C. T.; Sakkas, L. I.; Rasheed, M.; Artlett, C.; Jimenez, S. A. (2003)

Objective. To determine the prevalence of specific autoantibodies in a cohort of patients with systemic sclerosis (SSc) and a diagnosis of cancer, and to compare it to that in a group of patients with SSc who were never ...

A BAFF Receptor His159Tyr Mutation in Sjögren’s Syndrome-Related Lymphoproliferation

Papageorgiou A., Mavragani C.P., Nezos A., Zintzaras E., Quartuccio L., De Vita S., Koutsilieris M., Tzioufas A.G., Moutsopoulos H.M., Voulgarelis M. (2015)

Objective. To study the prevalence, clinical associations, and functional implications of the His159Tyr mutation of the BAFF receptor (BAFF-R) in patients with Sjögren’s syndrome (SS). Methods. The BAFF-R His159Tyr mutation ...

BDNF rs6265 (Val66Met) Polymorphism as a Risk Factor for Blepharospasm

Siokas V., Kardaras D., Aloizou A.-M., Asproudis I., Boboridis K.G., Papageorgiou E., Hadjigeorgiou G.M., Tsironi E.E., Dardiotis E. (2019)

A few genetic variants are implicated in the development of blepharospasm (BSP). The precise role of the rs6265 on the brain-derived neurotrophic factor (BDNF) gene on BSP remains controversial. The effect of rs6265 on BSP ...

Blood flow velocity comparison in the eye capillaries and postcapillary venules between normal pregnant and non-pregnant women

Moka S., Koutsiaris A.G., Garas A., Messinis I., Tachmitzi S.V., Giannoukas A., Tsironi E.E. (2020)

Background: There is no consensus on how much and at what diameters the blood flow velocity changes in the female microcirculation during normal pregnancy. Methods: A non-contact, digital slit-lamp biomicroscopy system was ...

Bone mineral density in vocational and professional ballet dancers

Amorim T., Koutedakis Y., Nevill A., Wyon M., Maia J., Machado J.C., Marques F., Metsios G.S., Flouris A.D., Adubeiro N., Nogueira L., Dimitriou L. (2017)

Summary: According to existing literature, bone health in ballet dancers is controversial. We have verified that, compared to controls, young female and male vocational ballet dancers have lower bone mineral density (BMD) ...

Brain volume dynamics in multiple sclerosis. A case-control study

Andravizou A., Artemiadis A., Bakirtzis C., Siokas V., Aloizou A.-M., Peristeri E., Kapsalaki E., Tsimourtou V., Hadjigeorgiou G.M., Dardiotis E. (2019)

Objectives: In this study, we aimed to explore the extent and clinical relevance of brain volume dynamics in relapsing remitting multiple sclerosis (RRMS). Methods: Sixty-three patients with RRMS with a disease duration ...

Breg Cells Are Numerically Decreased and Functionally Impaired in Patients with Systemic Sclerosis

Mavropoulos A., Simopoulou T., Varna A., Liaskos C., Katsiari C.G., Bogdanos D.P., Sakkas L.I. (2016)

Objective Breg cells, a regulatory cell subset that produces interleukin-10 (IL-10), play a significant role in suppressing autoimmune responses and preventing autoimmunity. This study was undertaken to examine the number ...

Buprenorphine and Methadone as Opioid Maintenance Treatments for Heroin-Addicted Patients Induce Oxidative Stress in Blood

Leventelis C., Goutzourelas N., Kortsinidou A., Spanidis Y., Toulia G., Kampitsi A., Tsitsimpikou C., Stagos D., Veskoukis A.S., Kouretas D. (2019)

Buprenorphine and methadone are two substances widely used in the substitution treatment of patients who are addicted to opioids. Although it is known that they partly act efficiently towards this direction, there is no ...