• Cell migration leads to spatially distinct but clonally related airway cancer precursors 

      Pipinikas, C. P.; Kiropoulos, T. S.; Teixeira, V. H.; Brown, J. M.; Varanou, A.; Falzon, M.; Capitanio, A.; Bottoms, S. E.; Carrol, B.; Navani, N.; McCaughan, F.; George, J. P.; Giangreco, A.; Wright, N. A.; McDonald, S. A. C.; Graham, T. A.; Janes, S. M. (2014)
      Background Squamous cell carcinoma of the lung is a common cancer with 95% mortality at 5 years. These cancers arise from preinvasive lesions, which have a natural history of development progressing through increasing ...
    • Epithelial-mesenchymal transition in non small-cell lung cancer 

      Tsoukalas N., Aravantinou-Fatorou E., Tolia M., Giaginis C., Galanopoulos M., Kiakou M., Kostakis I.D., Dana E., Vamvakaris I., Korogiannos A., Tsiambas E., Salemis N., Kyrgias G., Karameris A., Theocharis S. (2017)
      Background/Aim: Lung cancer is the first cause of cancer related deaths in both males and females. Epithelial-mesenchymal transition (EMT) is a reversible process by which epithelial cells transform to mesenchymal stem ...
    • Indoleamine 2,3-dioxygenase (IDO) expression in lung cancer 

      Karanikas, V.; Zamanakou, M.; Kerenidi, T.; Dahabreh, J.; Hevas, A.; Nakou, M.; Gourgoulianis, K. I.; Germenis, A. E. (2007)
      Background: The expression of indoleamine 2,3-dioxygenase (IDO) by tumor cells has been considered as a major tumor immune escape mechanism. The aim of this study was to investigate the expression of IDO in lung cancer ...
    • Lung cancer in patients with Idiopathic Pulmonary Fibrosis. A retrospective multicenter study in Greece 

      Tzouvelekis A., Karampitsakos T., Gomatou G., Bouros E., Tzilas V., Manali E., Tomos I., Trachalaki A., Kolilekas L., Korbila I., Tomos P., Chrysikos S., Gaga M., Daniil Z., Bardaka F., Papanikolaou I.C., Euthymiou C., Papakosta D., Steiropoulos P., Ntolios P., Tringidou R., Papiris S., Antoniou K., Bouros D. (2020)
      Background: Abundant evidence supports an association between Idiopathic Pulmonary Fibrosis (IPF) and lung cancer development. Data on diagnosis and management of patients with IPF and lung cancer are still scarce. Patients ...
    • Poly(A)-specific ribonuclease and Nocturnin in squamous cell lung cancer: Prognostic value and impact on gene expression 

      Maragozidis P., Papanastasi E., Scutelnic D., Totomi A., Kokkori I., Zarogiannis S.G., Kerenidi T., Gourgoulianis K.I., Balatsos N.A.A. (2015)
      Background: Lung cancer is the leading cause of cancer mortality worldwide, mainly due to late diagnosis, poor prognosis and tumor heterogeneity. Thus, the need for biomarkers that will aid classification, treatment and ...